Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine
Background and Purpose: Cancer is a serious public health concern, hence the determination of dacarbazine as a significant chemotherapeutic agent is very important. Experimental Approach: In the present work, we describe using a facile method to synthesize a nanocomposite of multi-walled carbon nan...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2025-01-01
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| Series: | ADMET and DMPK |
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| Online Access: | https://pub.iapchem.org/ojs/index.php/admet/article/view/2617 |
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| author | Somayeh Tajik Hadi Beitollahi Fariba Garkani Nejad Zahra Dourandish Samuel Adeloju |
| author_facet | Somayeh Tajik Hadi Beitollahi Fariba Garkani Nejad Zahra Dourandish Samuel Adeloju |
| author_sort | Somayeh Tajik |
| collection | DOAJ |
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Background and Purpose: Cancer is a serious public health concern, hence the determination of dacarbazine as a significant chemotherapeutic agent is very important. Experimental Approach: In the present work, we describe using a facile method to synthesize a nanocomposite of multi-walled carbon nanotubes (MWCNTs) and two-dimensional zeolitic imidazolate framework nanosheets (2D ZIF-L NSs). The resulting MWCNTs/2D ZIF-L NSs nanocomposite was characterized by field-emission scanning electron microscopy. The MWCNTs/2D ZIF-L NSs nanocomposite was subsequently used to modify a screen-printed carbon electrode (SPCE) to achieve an electrochemical sensing platform for the detection of dacarbazine.
Conclusion: This detection method can be used as a valuable tool in the analysis of pharmaceutical formulations to bring benefits in the cancer treatment.
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| format | Article |
| id | doaj-art-93c5c3c79dcb421f84386cb61bfdd9d2 |
| institution | Kabale University |
| issn | 1848-7718 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | ADMET and DMPK |
| spelling | doaj-art-93c5c3c79dcb421f84386cb61bfdd9d22025-01-26T07:47:31ZengInternational Association of Physical Chemists (IAPC)ADMET and DMPK1848-77182025-01-0110.5599/admet.2617Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazineSomayeh Tajik0Hadi Beitollahi1Fariba Garkani Nejad2Zahra Dourandish3Samuel Adeloju4NanoBioelectrochemistry Research Center, Bam University of Medical Sciences, Bam, IranFraduate University of Advanced Technology, Kerman, IranGraduate University of Advanced Technology, Kerman, IranGraduate University of Advanced Technology, Kerman, IranSchool of Chemistry, Monash University, Clayton, Victoria 3800, Australia Background and Purpose: Cancer is a serious public health concern, hence the determination of dacarbazine as a significant chemotherapeutic agent is very important. Experimental Approach: In the present work, we describe using a facile method to synthesize a nanocomposite of multi-walled carbon nanotubes (MWCNTs) and two-dimensional zeolitic imidazolate framework nanosheets (2D ZIF-L NSs). The resulting MWCNTs/2D ZIF-L NSs nanocomposite was characterized by field-emission scanning electron microscopy. The MWCNTs/2D ZIF-L NSs nanocomposite was subsequently used to modify a screen-printed carbon electrode (SPCE) to achieve an electrochemical sensing platform for the detection of dacarbazine. Conclusion: This detection method can be used as a valuable tool in the analysis of pharmaceutical formulations to bring benefits in the cancer treatment. https://pub.iapchem.org/ojs/index.php/admet/article/view/2617Screen-printed carbon electrodecarbon nanostructuresTwo-dimensional metal-organic frameworkscancer diseasechemotherapypharmaceutical compounds |
| spellingShingle | Somayeh Tajik Hadi Beitollahi Fariba Garkani Nejad Zahra Dourandish Samuel Adeloju Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine ADMET and DMPK Screen-printed carbon electrode carbon nanostructures Two-dimensional metal-organic frameworks cancer disease chemotherapy pharmaceutical compounds |
| title | Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine |
| title_full | Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine |
| title_fullStr | Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine |
| title_full_unstemmed | Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine |
| title_short | Electrochemical sensor based on multi-walled carbon nanotubes and two-dimensional zeolitic imidazolate framework nanosheets: Application in determining dacarbazine |
| title_sort | electrochemical sensor based on multi walled carbon nanotubes and two dimensional zeolitic imidazolate framework nanosheets application in determining dacarbazine |
| topic | Screen-printed carbon electrode carbon nanostructures Two-dimensional metal-organic frameworks cancer disease chemotherapy pharmaceutical compounds |
| url | https://pub.iapchem.org/ojs/index.php/admet/article/view/2617 |
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