Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy
Cowden syndrome is an uncommon, autosomal dominant disease characterized by multiple hamartomas and hyperplastic lesions in the skin, mucous membrane, brain, breast, thyroid, and gastrointestinal tract. About 30% of Cowden syndrome cases are reportedly complicated by malignant diseases. Hamartomatou...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/475705 |
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| author | Keita Saito Eiki Nomura Yu Sasaki Yasuhiko Abe Nana Kanno Naoko Mizumoto Rika Shibuya Kazuhiro Sakuta Makoto Yagi Kazuya Yoshizawa Daisuke Iwano Takeshi Sato Shoichi Nishise Yoshiyuki Ueno |
| author_facet | Keita Saito Eiki Nomura Yu Sasaki Yasuhiko Abe Nana Kanno Naoko Mizumoto Rika Shibuya Kazuhiro Sakuta Makoto Yagi Kazuya Yoshizawa Daisuke Iwano Takeshi Sato Shoichi Nishise Yoshiyuki Ueno |
| author_sort | Keita Saito |
| collection | DOAJ |
| description | Cowden syndrome is an uncommon, autosomal dominant disease characterized by multiple hamartomas and hyperplastic lesions in the skin, mucous membrane, brain, breast, thyroid, and gastrointestinal tract. About 30% of Cowden syndrome cases are reportedly complicated by malignant diseases. Hamartomatous polyps occur throughout the gastrointestinal tract, the most common sites being the stomach, colon, esophagus, and duodenum. Small bowel polyps can occur in Cowden syndrome; however, they are difficult to detect by conventional examination, including double-contrast X-ray study. Here, we report three cases of Cowden syndrome with small bowel polyps, which were detected by capsule endoscopy. The small bowel polyps of Cowden syndrome frequently occur at the oral end of the small bowel, especially in the duodenum and jejunum, and their color is similar to that of the surrounding mucosa; additionally, the polyps are relatively small (2–5 mm). Capsule endoscopy is useful for detecting small bowel polyps in Cowden syndrome. |
| format | Article |
| id | doaj-art-939d83c93e31452187a6f387eff04655 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-939d83c93e31452187a6f387eff046552025-02-03T01:25:52ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362015-01-01201510.1155/2015/475705475705Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule EndoscopyKeita Saito0Eiki Nomura1Yu Sasaki2Yasuhiko Abe3Nana Kanno4Naoko Mizumoto5Rika Shibuya6Kazuhiro Sakuta7Makoto Yagi8Kazuya Yoshizawa9Daisuke Iwano10Takeshi Sato11Shoichi Nishise12Yoshiyuki Ueno13Department of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanDepartment of Gastroenterology, Faculty of Medicine, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, JapanCowden syndrome is an uncommon, autosomal dominant disease characterized by multiple hamartomas and hyperplastic lesions in the skin, mucous membrane, brain, breast, thyroid, and gastrointestinal tract. About 30% of Cowden syndrome cases are reportedly complicated by malignant diseases. Hamartomatous polyps occur throughout the gastrointestinal tract, the most common sites being the stomach, colon, esophagus, and duodenum. Small bowel polyps can occur in Cowden syndrome; however, they are difficult to detect by conventional examination, including double-contrast X-ray study. Here, we report three cases of Cowden syndrome with small bowel polyps, which were detected by capsule endoscopy. The small bowel polyps of Cowden syndrome frequently occur at the oral end of the small bowel, especially in the duodenum and jejunum, and their color is similar to that of the surrounding mucosa; additionally, the polyps are relatively small (2–5 mm). Capsule endoscopy is useful for detecting small bowel polyps in Cowden syndrome.http://dx.doi.org/10.1155/2015/475705 |
| spellingShingle | Keita Saito Eiki Nomura Yu Sasaki Yasuhiko Abe Nana Kanno Naoko Mizumoto Rika Shibuya Kazuhiro Sakuta Makoto Yagi Kazuya Yoshizawa Daisuke Iwano Takeshi Sato Shoichi Nishise Yoshiyuki Ueno Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy Case Reports in Gastrointestinal Medicine |
| title | Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy |
| title_full | Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy |
| title_fullStr | Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy |
| title_full_unstemmed | Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy |
| title_short | Characteristics of Small Bowel Polyps Detected in Cowden Syndrome by Capsule Endoscopy |
| title_sort | characteristics of small bowel polyps detected in cowden syndrome by capsule endoscopy |
| url | http://dx.doi.org/10.1155/2015/475705 |
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