Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity
Abstract Objective Autism spectrum disorder (ASD) is characterized by high rates of comorbidity with other mental disorders, including anxiety disorders and obsessive–compulsive disorder. Beyond a mere concept of comorbidity, recent literature is speculating the existence of a neurodevelopmental nat...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12888-024-06340-8 |
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| author | Liliana Dell’Osso Giulia Amatori Chiara Bonelli Benedetta Nardi Enrico Massimetti Ivan Mirko Cremone Stefano Pini Barbara Carpita |
| author_facet | Liliana Dell’Osso Giulia Amatori Chiara Bonelli Benedetta Nardi Enrico Massimetti Ivan Mirko Cremone Stefano Pini Barbara Carpita |
| author_sort | Liliana Dell’Osso |
| collection | DOAJ |
| description | Abstract Objective Autism spectrum disorder (ASD) is characterized by high rates of comorbidity with other mental disorders, including anxiety disorders and obsessive–compulsive disorder. Beyond a mere concept of comorbidity, recent literature is speculating the existence of a neurodevelopmental nature of such mental disorders. The aim of the study is to investigate the distribution of social-phobic, obsessive–compulsive and panic-agoraphobic traits within a sample of individuals with ASD, social anxiety disorder (SAD), obsessive–compulsive disorder (OCD) and panic disorder (PD). Methods 40 participants with ASD, 40 with SAD, 40 with OCD, 40 with PD and 50 HC were assessed with the Social Anxiety Spectrum—Short Version (SHY-SV) questionnaire, the Obsessive—Compulsive Spectrum—Short Version (OBS-SV) questionnaire and the Panic Agoraphobic Spectrum—Short Version (PAS-SV) questionnaire. Statistical analyses included Kruskal–Wallis test and Chi-square test. Results When analyzing SHY-SV scores, the SAD group obtained the highest scores, with individuals with ASD following closely, significantly surpassing the scores of the remaining diagnostic groups. In the examination of OBS-SV questionnaire scores, individuals with ASD once again secured the second-highest scores, trailing only the OCD group. These scores were notably higher than those of both the PD group and healthy controls. In the analysis of PAS-SV scores, the ASD group once again achieved the highest scores after the PD individuals, although this time the difference was not statistically significant compared to the other diagnostic groups. Discussion These findings highlight the central role of the autism spectrum in SAD and OCD diagnoses. They provide support for the hypotheses of a neurodevelopmental basis for social anxiety and OCD, contributing to the growing body of evidence supporting a dimensional and interconnected view of mental health conditions. |
| format | Article |
| id | doaj-art-9394605908df46438c7440bc79e84224 |
| institution | Kabale University |
| issn | 1471-244X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj-art-9394605908df46438c7440bc79e842242025-01-19T12:34:28ZengBMCBMC Psychiatry1471-244X2025-01-0125111010.1186/s12888-024-06340-8Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidityLiliana Dell’Osso0Giulia Amatori1Chiara Bonelli2Benedetta Nardi3Enrico Massimetti4Ivan Mirko Cremone5Stefano Pini6Barbara Carpita7Department of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaDepartment of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaDepartment of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaDepartment of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaDepartment of Psychiatry, North-Western Tuscany Region NHS Local Health UnitDepartment of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaDepartment of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaDepartment of Clinical and Experimental Medicine, Section of Psychiatry, University of PisaAbstract Objective Autism spectrum disorder (ASD) is characterized by high rates of comorbidity with other mental disorders, including anxiety disorders and obsessive–compulsive disorder. Beyond a mere concept of comorbidity, recent literature is speculating the existence of a neurodevelopmental nature of such mental disorders. The aim of the study is to investigate the distribution of social-phobic, obsessive–compulsive and panic-agoraphobic traits within a sample of individuals with ASD, social anxiety disorder (SAD), obsessive–compulsive disorder (OCD) and panic disorder (PD). Methods 40 participants with ASD, 40 with SAD, 40 with OCD, 40 with PD and 50 HC were assessed with the Social Anxiety Spectrum—Short Version (SHY-SV) questionnaire, the Obsessive—Compulsive Spectrum—Short Version (OBS-SV) questionnaire and the Panic Agoraphobic Spectrum—Short Version (PAS-SV) questionnaire. Statistical analyses included Kruskal–Wallis test and Chi-square test. Results When analyzing SHY-SV scores, the SAD group obtained the highest scores, with individuals with ASD following closely, significantly surpassing the scores of the remaining diagnostic groups. In the examination of OBS-SV questionnaire scores, individuals with ASD once again secured the second-highest scores, trailing only the OCD group. These scores were notably higher than those of both the PD group and healthy controls. In the analysis of PAS-SV scores, the ASD group once again achieved the highest scores after the PD individuals, although this time the difference was not statistically significant compared to the other diagnostic groups. Discussion These findings highlight the central role of the autism spectrum in SAD and OCD diagnoses. They provide support for the hypotheses of a neurodevelopmental basis for social anxiety and OCD, contributing to the growing body of evidence supporting a dimensional and interconnected view of mental health conditions.https://doi.org/10.1186/s12888-024-06340-8Autism spectrum disorderSocial anxiety disorderObsessive–compulsive disorderPanic disorder |
| spellingShingle | Liliana Dell’Osso Giulia Amatori Chiara Bonelli Benedetta Nardi Enrico Massimetti Ivan Mirko Cremone Stefano Pini Barbara Carpita Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity BMC Psychiatry Autism spectrum disorder Social anxiety disorder Obsessive–compulsive disorder Panic disorder |
| title | Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity |
| title_full | Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity |
| title_fullStr | Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity |
| title_full_unstemmed | Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity |
| title_short | Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity |
| title_sort | autism spectrum disorder social anxiety and obsessive compulsive disorders beyond the comorbidity |
| topic | Autism spectrum disorder Social anxiety disorder Obsessive–compulsive disorder Panic disorder |
| url | https://doi.org/10.1186/s12888-024-06340-8 |
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