Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition?
Helicobacter pylori (Hp) is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of ch...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2018/6237239 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832547096674172928 |
|---|---|
| author | Giovanni Bruno Giulia Rocco Piera Zaccari Barbara Porowska Maria Teresa Mascellino Carola Severi |
| author_facet | Giovanni Bruno Giulia Rocco Piera Zaccari Barbara Porowska Maria Teresa Mascellino Carola Severi |
| author_sort | Giovanni Bruno |
| collection | DOAJ |
| description | Helicobacter pylori (Hp) is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Hp colonization modifies the composition of gastric microbiota that could drive the development of gastric disorders. Currently, an emerging problem in Hp treatment is represented by the increasing rate of antimicrobial therapy resistance. In this context, the search for adjuvant agents can be very useful to overcome this issue and probiotics administration can represent a valid option. The aim of this review is to describe the gastric microbiota changes during Hp colonization, the mechanisms of action, and a possible role of probiotics in the treatment of this infection. |
| format | Article |
| id | doaj-art-9393ff9442064a60b7ffe5f69362b169 |
| institution | Kabale University |
| issn | 1712-9532 1918-1493 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-9393ff9442064a60b7ffe5f69362b1692025-02-03T06:46:12ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932018-01-01201810.1155/2018/62372396237239Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition?Giovanni Bruno0Giulia Rocco1Piera Zaccari2Barbara Porowska3Maria Teresa Mascellino4Carola Severi5Department of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University, Rome, ItalyDepartment of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University, Rome, ItalyDepartment of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University, Rome, ItalyDepartment of Cardio-Thoracic, Vascular Surgery and Transplants, Sapienza University, Rome, ItalyDepartment of Public Health and Infectious Diseases, Sapienza University, Rome, ItalyDepartment of Internal Medicine and Medical Specialties, Gastroenterology Unit, Sapienza University, Rome, ItalyHelicobacter pylori (Hp) is responsible for one of the most common infections in the world. The prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Hp colonization modifies the composition of gastric microbiota that could drive the development of gastric disorders. Currently, an emerging problem in Hp treatment is represented by the increasing rate of antimicrobial therapy resistance. In this context, the search for adjuvant agents can be very useful to overcome this issue and probiotics administration can represent a valid option. The aim of this review is to describe the gastric microbiota changes during Hp colonization, the mechanisms of action, and a possible role of probiotics in the treatment of this infection.http://dx.doi.org/10.1155/2018/6237239 |
| spellingShingle | Giovanni Bruno Giulia Rocco Piera Zaccari Barbara Porowska Maria Teresa Mascellino Carola Severi Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition? Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition? |
| title_full | Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition? |
| title_fullStr | Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition? |
| title_full_unstemmed | Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition? |
| title_short | Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition? |
| title_sort | helicobacter pylori infection and gastric dysbiosis can probiotics administration be useful to treat this condition |
| url | http://dx.doi.org/10.1155/2018/6237239 |
| work_keys_str_mv | AT giovannibruno helicobacterpyloriinfectionandgastricdysbiosiscanprobioticsadministrationbeusefultotreatthiscondition AT giuliarocco helicobacterpyloriinfectionandgastricdysbiosiscanprobioticsadministrationbeusefultotreatthiscondition AT pierazaccari helicobacterpyloriinfectionandgastricdysbiosiscanprobioticsadministrationbeusefultotreatthiscondition AT barbaraporowska helicobacterpyloriinfectionandgastricdysbiosiscanprobioticsadministrationbeusefultotreatthiscondition AT mariateresamascellino helicobacterpyloriinfectionandgastricdysbiosiscanprobioticsadministrationbeusefultotreatthiscondition AT carolaseveri helicobacterpyloriinfectionandgastricdysbiosiscanprobioticsadministrationbeusefultotreatthiscondition |