HIV Vaccine Research: The Challenge and the Way Forward
Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a worldwide epidemic, with over 35 million people infected currently. Therefore, the development of a safe and effective HIV-1 vaccine is on top of the global health priority. In the past few years, there have been many p...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2015/503978 |
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| _version_ | 1832548067753066496 |
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| author | Hai-Bo Wang Qiu-Hua Mo Ze Yang |
| author_facet | Hai-Bo Wang Qiu-Hua Mo Ze Yang |
| author_sort | Hai-Bo Wang |
| collection | DOAJ |
| description | Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a worldwide epidemic, with over 35 million people infected currently. Therefore, the development of a safe and effective HIV-1 vaccine is on top of the global health priority. In the past few years, there have been many promising advances in the prevention of HIV/AIDS, among which the RV144 Thai trial has been encouraging and suggests optimization of the current vaccine strategies or search for novel strategies. Here we reviewed the brief history of HIV-1 vaccine, analyzed key challenges existing now, and illustrated future research priority/directions for a therapeutic or prophylactic HIV-1 vaccine, with the hope of accelerating the speed of vaccine development. We believe that an effective HIV-1 vaccine, together with other prevention approaches, will bring an end to this epidemic in the near future. |
| format | Article |
| id | doaj-art-93782d551ec34b26bc0ef4910a5ee5e4 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-93782d551ec34b26bc0ef4910a5ee5e42025-02-03T06:42:25ZengWileyJournal of Immunology Research2314-88612314-71562015-01-01201510.1155/2015/503978503978HIV Vaccine Research: The Challenge and the Way ForwardHai-Bo Wang0Qiu-Hua Mo1Ze Yang2Zhuhai International Travel Healthcare Center, Zhuhai Entry-Exit Inspection and Quarantine Bureau, Zhuhai, Guangdong 519020, ChinaZhuhai International Travel Healthcare Center, Zhuhai Entry-Exit Inspection and Quarantine Bureau, Zhuhai, Guangdong 519020, ChinaZhuhai International Travel Healthcare Center, Zhuhai Entry-Exit Inspection and Quarantine Bureau, Zhuhai, Guangdong 519020, ChinaHuman immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a worldwide epidemic, with over 35 million people infected currently. Therefore, the development of a safe and effective HIV-1 vaccine is on top of the global health priority. In the past few years, there have been many promising advances in the prevention of HIV/AIDS, among which the RV144 Thai trial has been encouraging and suggests optimization of the current vaccine strategies or search for novel strategies. Here we reviewed the brief history of HIV-1 vaccine, analyzed key challenges existing now, and illustrated future research priority/directions for a therapeutic or prophylactic HIV-1 vaccine, with the hope of accelerating the speed of vaccine development. We believe that an effective HIV-1 vaccine, together with other prevention approaches, will bring an end to this epidemic in the near future.http://dx.doi.org/10.1155/2015/503978 |
| spellingShingle | Hai-Bo Wang Qiu-Hua Mo Ze Yang HIV Vaccine Research: The Challenge and the Way Forward Journal of Immunology Research |
| title | HIV Vaccine Research: The Challenge and the Way Forward |
| title_full | HIV Vaccine Research: The Challenge and the Way Forward |
| title_fullStr | HIV Vaccine Research: The Challenge and the Way Forward |
| title_full_unstemmed | HIV Vaccine Research: The Challenge and the Way Forward |
| title_short | HIV Vaccine Research: The Challenge and the Way Forward |
| title_sort | hiv vaccine research the challenge and the way forward |
| url | http://dx.doi.org/10.1155/2015/503978 |
| work_keys_str_mv | AT haibowang hivvaccineresearchthechallengeandthewayforward AT qiuhuamo hivvaccineresearchthechallengeandthewayforward AT zeyang hivvaccineresearchthechallengeandthewayforward |