Isolated Internal Ophthalmoplegia following Herpes Zoster Ophthalmicus

Herpes zoster ophthalmicus (HZO) is a disease involving the ophthalmic division of the trigeminal nerve due to the reactivation of the latent varicella-zoster virus in the dorsal root ganglion, commonly affecting people with compromised immunity and advancing age. It can cause a myriad of ocular man...

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Bibliographic Details
Main Authors: Neha Pathak, Gagan Deep Kaur, Virendra Agrawal, Amit Mishra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/DLJO.DLJO_164_24
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Summary:Herpes zoster ophthalmicus (HZO) is a disease involving the ophthalmic division of the trigeminal nerve due to the reactivation of the latent varicella-zoster virus in the dorsal root ganglion, commonly affecting people with compromised immunity and advancing age. It can cause a myriad of ocular manifestations. Total external and internal ophthalmoplegia occurs in 10%–30% of cases. Isolated third, fourth, and sixth cranial nerve palsies have also been reported. However, isolated pupillary paralysis as a solitary cranial nerve complication is rare. The suggested etiopathogenesis is acute ganglionic/postganglionic neuron denervation injury. We present one such case showing persistent tonic pupil even at 15 months following the onset of HZO despite the recovery in inflammation with treatment.
ISSN:0972-0200
2454-2784