Associations among immunophenotype, plasma metabolites, and benign prostatic hyperplasia: a mediation Mendelian randomization study

Associations among immunophenotype, plasma metabolites, and benign prostatic hyperplasia: a mediation Mendelian randomization study

Objective To explore the potential causal relationship between immune cells, plasma metabolites and benign prostatic hyperplasia (BPH) and the mediating role of plasma metabolism by using the mediated Mendelian randomization (MR) method. Methods Two-sample bidirectional MR analysis was used to predi...

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Bibliographic Details
Main Authors: FAN Jiuming, ZHAO Yiqiao, JIA Haichang, WANG Tiankun, HAN Yutong, QIN Zihao, CHEN Ping, ZENG Xiantao
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2025-01-01
Series:Yixue xinzhi zazhi
Subjects:
benign prostatic hyperplasia
mendelian randomization
immunophenotypes
plasma metabolites
exposure-mediator-outcome pathway
mediation analysis
Online Access:https://yxxz.whuznhmedj.com/futureApi/storage/attach/2501/EnCVgvynyKWjsSDUUg7H31NtLA0YzYcDodvnaDya.pdf
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