Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study

Background. Skin biopsy is an established method for allying the dermatologist in overcoming the diagnostic dilemmas which occur during consultations. However neither do all skin biopsies produce a conclusive diagnosis nor the dermatologists routinely perform this procedure to every patient they con...

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Main Authors: Chrysovalantis Korfitis, Stamatis Gregoriou, Christina Antoniou, Andreas D. Katsambas, Dimitris Rigopoulos
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/734906
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author Chrysovalantis Korfitis
Stamatis Gregoriou
Christina Antoniou
Andreas D. Katsambas
Dimitris Rigopoulos
author_facet Chrysovalantis Korfitis
Stamatis Gregoriou
Christina Antoniou
Andreas D. Katsambas
Dimitris Rigopoulos
author_sort Chrysovalantis Korfitis
collection DOAJ
description Background. Skin biopsy is an established method for allying the dermatologist in overcoming the diagnostic dilemmas which occur during consultations. However neither do all skin biopsies produce a conclusive diagnosis nor the dermatologists routinely perform this procedure to every patient they consult. The aim of this study was to investigate the favourable clinical diagnoses set by dermatologists when performing skin biopsy, the diagnoses reached by the dermatopathologists after microscopic examination, and the relationship between them and finally to comment on the instances that skin biopsy fails to fulfill the diagnostic task. Methods. Six thousand eight hundred and sixteen biopsy specimens were reviewed and descriptive statistics were performed. Results. The mean age of the patients was 54.58±0.26 years, the most common site of biopsy was the head and neck (38.3%), the most frequently proposed clinical diagnoses included malignancies (19.28%), and the most prevalent pathological diagnosis was epitheliomas (21.9%). After microscopic examination, a specific histological diagnosis was proposed in 83.29% of the cases and a consensus between clinical and histological diagnoses was observed in 68% of them. Conclusions. Although there are cases that skin biopsy exhibits diagnostic inefficiency, it remains a valuable aid for the dermatology clinical practice.
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spelling doaj-art-93364f78be3446219dfe7fee8dbd738f2025-02-03T01:00:51ZengWileyDermatology Research and Practice1687-61051687-61132014-01-01201410.1155/2014/734906734906Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort StudyChrysovalantis Korfitis0Stamatis Gregoriou1Christina Antoniou2Andreas D. Katsambas3Dimitris Rigopoulos4Department of Dermatology, Veterans Administration Hospital, 10-12 Monis Petraki Street, 11521 Athens, GreeceDepartment of Dermatology, Attikon Hospital, 1 Rimini Street, Haidari, 12462 Athens, GreeceDepartment of Dermatology, Andreas Sygros Hospital, 5 I. Dragoumi Street, 16121 Athens, GreeceDepartment of Dermatology, Andreas Sygros Hospital, 5 I. Dragoumi Street, 16121 Athens, GreeceDepartment of Dermatology, Attikon Hospital, 1 Rimini Street, Haidari, 12462 Athens, GreeceBackground. Skin biopsy is an established method for allying the dermatologist in overcoming the diagnostic dilemmas which occur during consultations. However neither do all skin biopsies produce a conclusive diagnosis nor the dermatologists routinely perform this procedure to every patient they consult. The aim of this study was to investigate the favourable clinical diagnoses set by dermatologists when performing skin biopsy, the diagnoses reached by the dermatopathologists after microscopic examination, and the relationship between them and finally to comment on the instances that skin biopsy fails to fulfill the diagnostic task. Methods. Six thousand eight hundred and sixteen biopsy specimens were reviewed and descriptive statistics were performed. Results. The mean age of the patients was 54.58±0.26 years, the most common site of biopsy was the head and neck (38.3%), the most frequently proposed clinical diagnoses included malignancies (19.28%), and the most prevalent pathological diagnosis was epitheliomas (21.9%). After microscopic examination, a specific histological diagnosis was proposed in 83.29% of the cases and a consensus between clinical and histological diagnoses was observed in 68% of them. Conclusions. Although there are cases that skin biopsy exhibits diagnostic inefficiency, it remains a valuable aid for the dermatology clinical practice.http://dx.doi.org/10.1155/2014/734906
spellingShingle Chrysovalantis Korfitis
Stamatis Gregoriou
Christina Antoniou
Andreas D. Katsambas
Dimitris Rigopoulos
Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study
Dermatology Research and Practice
title Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study
title_full Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study
title_fullStr Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study
title_full_unstemmed Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study
title_short Skin Biopsy in the Context of Dermatological Diagnosis: A Retrospective Cohort Study
title_sort skin biopsy in the context of dermatological diagnosis a retrospective cohort study
url http://dx.doi.org/10.1155/2014/734906
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