A Novel Galantamine–Curcumin Hybrid Inhibits Butyrylcholinesterase: A Molecular Dynamics Study
Cholinesterases are enzymes that break down the neurotransmitter acetylcholine in the nervous system. The two main types are acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). AChE inhibitors are used to treat Alzheimer’s disease by increasing acetylcholine levels. BChE activity increases...
Saved in:
| Main Authors: | Evdokiya Salamanova, Mariyana Atanasova, Irini Doytchinova |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Chemistry |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2624-8549/6/6/100 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A galantamine–curcumin hybrid lacks the depressant side effect of acetylcholinesterase inhibitors
by: Ivanka Kostadinova, et al.
Published: (2024-12-01) -
Targeting cholinergic dysfunction in Alzheimer’s disease: Development of next-generation galantamine derivatives
by: Zahra Keshavarz, et al.
Published: (2025-09-01) -
Galantamine-Memantine Combination in the Treatment of Parkinson’s Disease Dementia
by: Emma D. Frost, et al.
Published: (2024-11-01) -
Ligands affinity for regulatory sites of human acetylcholesterase and butyrylcholinesterase: A comparative bioinformatic analysis
by: A.R. Mukhametgalieva, et al.
Published: (2021-03-01) -
Heterostilbene Carbamates with Selective and Remarkable Butyrylcholinesterase Inhibition: Computational Study and Physico-Chemical Properties
by: Anamarija Raspudić, et al.
Published: (2025-06-01)