Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review

Background. Zoster-associated pain (ZAP) is often refractory to conventional treatments and can seriously affect patients’ physical and mental health. High-voltage pulsed radio frequency (H-PRF) is a new method for treating ZAP with pulse voltages above 60 V or even up to 100 V. The purpose of this...

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Main Authors: Yinghao Song, Ziheng Yu, Jingjing Guan, Haisheng Wu, Jinglang Zhang, Liu Qiaoling, Min Yuan, Xinzhi Cheng, Bingyu Ling
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Anesthesiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2023/8479293
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author Yinghao Song
Ziheng Yu
Jingjing Guan
Haisheng Wu
Jinglang Zhang
Liu Qiaoling
Min Yuan
Xinzhi Cheng
Bingyu Ling
author_facet Yinghao Song
Ziheng Yu
Jingjing Guan
Haisheng Wu
Jinglang Zhang
Liu Qiaoling
Min Yuan
Xinzhi Cheng
Bingyu Ling
author_sort Yinghao Song
collection DOAJ
description Background. Zoster-associated pain (ZAP) is often refractory to conventional treatments and can seriously affect patients’ physical and mental health. High-voltage pulsed radio frequency (H-PRF) is a new method for treating ZAP with pulse voltages above 60 V or even up to 100 V. The purpose of this paper was to conduct a systematic review and meta-analysis to evaluate the efficacy of H-PRF in the management of ZAP. Methods. PubMed, Embase, and the Cochrane library were searched from their inception to June 2022 to identify controlled trials which evaluated the effectiveness of H-PRF compared with standard PRF and sham operations. The primary outcome was pain scores at different treatment times. The secondary outcomes included SF-36 scores, rescue analgesic dose, and side effects. Results. We reviewed 6 randomized controlled trials involving 428 patients. There was no significant difference between the H-PRF and standard PRF pain scores at 1 week after surgery and the sham operation group at 1 month. At 1, 3, and 6 months, the H-PRF group had better pain score than the standard PRF group, and at 3 months, the pain score was better than the sham operation group. The H-PRF group showed improvement in the SF-36 score, and there were no significant complications in the H-PRF group. Conclusions. H-PRF is an effective and safe treatment method that has better effects in relieving pain and improving the quality of life and physical and mental health. Although H-PRF provides pain relief rates comparable to those of the control group in the early stages, it remains the preferred and alternative treatment for relieving herpes zoster-related pain.
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spelling doaj-art-932164fea33f42eea474d857a7e312d72025-02-03T06:47:44ZengWileyAnesthesiology Research and Practice1687-69702023-01-01202310.1155/2023/8479293Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic ReviewYinghao Song0Ziheng Yu1Jingjing Guan2Haisheng Wu3Jinglang Zhang4Liu Qiaoling5Min Yuan6Xinzhi Cheng7Bingyu Ling8Department of PainDepartment of PainDepartment of PainDepartment of PainDepartment of PainDepartment of PainDepartment of PainDepartment of PainDepartment of EmergencyBackground. Zoster-associated pain (ZAP) is often refractory to conventional treatments and can seriously affect patients’ physical and mental health. High-voltage pulsed radio frequency (H-PRF) is a new method for treating ZAP with pulse voltages above 60 V or even up to 100 V. The purpose of this paper was to conduct a systematic review and meta-analysis to evaluate the efficacy of H-PRF in the management of ZAP. Methods. PubMed, Embase, and the Cochrane library were searched from their inception to June 2022 to identify controlled trials which evaluated the effectiveness of H-PRF compared with standard PRF and sham operations. The primary outcome was pain scores at different treatment times. The secondary outcomes included SF-36 scores, rescue analgesic dose, and side effects. Results. We reviewed 6 randomized controlled trials involving 428 patients. There was no significant difference between the H-PRF and standard PRF pain scores at 1 week after surgery and the sham operation group at 1 month. At 1, 3, and 6 months, the H-PRF group had better pain score than the standard PRF group, and at 3 months, the pain score was better than the sham operation group. The H-PRF group showed improvement in the SF-36 score, and there were no significant complications in the H-PRF group. Conclusions. H-PRF is an effective and safe treatment method that has better effects in relieving pain and improving the quality of life and physical and mental health. Although H-PRF provides pain relief rates comparable to those of the control group in the early stages, it remains the preferred and alternative treatment for relieving herpes zoster-related pain.http://dx.doi.org/10.1155/2023/8479293
spellingShingle Yinghao Song
Ziheng Yu
Jingjing Guan
Haisheng Wu
Jinglang Zhang
Liu Qiaoling
Min Yuan
Xinzhi Cheng
Bingyu Ling
Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review
Anesthesiology Research and Practice
title Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review
title_full Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review
title_fullStr Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review
title_full_unstemmed Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review
title_short Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review
title_sort efficacy of high voltage pulsed radiofrequency in zoster associated pain a meta analysis and systematic review
url http://dx.doi.org/10.1155/2023/8479293
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