Synergistic effects of PS-NPs and Cd on ovarian toxicity in adolescent rats: Ferroptosis by induction of mitochondrial redox imbalance via the SIRT3-SOD2/Gpx4 pathway

Synergistic effects of PS-NPs and Cd on ovarian toxicity in adolescent rats: Ferroptosis by induction of mitochondrial redox imbalance via the SIRT3-SOD2/Gpx4 pathway

Nanoplastics (NPs) are an emerging class of pollutants. They can act as a“Trojan horse” to change the bioavailability and toxicity of heavy metals in the environment. However, research on the combined toxicity of heavy metals and NPs is scarce, especially during the critical developmental period of...

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Bibliographic Details
Main Authors: Hua Wu, Lihua Feng, Huang Wu, Lihong Wang, Hengyi Xu, Fen Fu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PS-NPs
Cd
Adolescent ovarian development
Ferroptosis
SIRT3-SOD2/Gpx4 pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324016981
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