A new NCL-targeting aptamer-drug conjugate as a promising therapy against esophageal cancer
Abstract Esophageal cancer (EC) is one of the most common highly malignant tumors of the digestive system, with a poor prognosis under current treatment regimens. Nucleolin (NCL) is overexpressed in many tumors, and drugs specifically targeting NCL may offer a promising strategy for treating esophag...
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Main Authors: | Xue Zheng, Ying Wang, Huaiyu Duan, Junqi Hou, Shiming He |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-025-03127-1 |
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