Total Adiponectin Is Inversely Associated with Platelet Activation and CHA2DS2-VASc Score in Anticoagulated Patients with Atrial Fibrillation

Total Adiponectin Is Inversely Associated with Platelet Activation and CHA2DS2-VASc Score in Anticoagulated Patients with Atrial Fibrillation

Background. Adiponectin (APN) possesses anti-inflammatory and antiatherogenic effects. Atrial fibrillation (AF) is burdened by enhanced systemic inflammation and platelet activation, as documented by increased blood levels of soluble CD40L (sCD40L). The interplay between APN and platelet activation...

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Main Authors: Roberto Carnevale, Daniele Pastori, Mariangela Peruzzi, Elena De Falco, Isotta Chimenti, Giuseppe Biondi-Zoccai, Ernesto Greco, Antonino G. M. Marullo, Cristina Nocella, Francesco Violi, Pasquale Pignatelli, Camilla Calvieri, Giacomo Frati
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/908901
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