Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment
Abstract Background When faced with treatment options, patients are asked to participate in decision‐making. We sought to determine which treatment aspects matter most for individuals treated for muscle invasive bladder cancer (MIBC), with an aim to improve understanding of patient preferences and w...
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| Format: | Article |
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Wiley
2024-11-01
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| Series: | BJUI Compass |
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| Online Access: | https://doi.org/10.1002/bco2.443 |
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| author | Liam Mannion Verity Watson Vinod Mullassery Rajesh Nair Thomas Charlton Margaret Northover Deborah Enting Mieke Van Hemelrijck Muhammad Shamim Khan Ramesh Thurairaja Suzanne Amery Kathryn Chatterton Kate Smith Simon Hughes |
| author_facet | Liam Mannion Verity Watson Vinod Mullassery Rajesh Nair Thomas Charlton Margaret Northover Deborah Enting Mieke Van Hemelrijck Muhammad Shamim Khan Ramesh Thurairaja Suzanne Amery Kathryn Chatterton Kate Smith Simon Hughes |
| author_sort | Liam Mannion |
| collection | DOAJ |
| description | Abstract Background When faced with treatment options, patients are asked to participate in decision‐making. We sought to determine which treatment aspects matter most for individuals treated for muscle invasive bladder cancer (MIBC), with an aim to improve understanding of patient preferences and what trade‐offs patients are willing to accept. Our study consisted of a discrete choice experiment (DCE): a type of questionnaire used to elicit preferences in the absence of real‐world choice. Methods The DCE had five attributives, each with three levels. Participants were asked to complete a questionnaire in which they were asked to choose between two hypothetical MIBC treatments. The data were analysed using a conditional logit model, and preferences for, and trade‐offs between, attributes were estimated. Results We recruited patients with MIBC who had either already completed, were undergoing or had yet to commence radical treatment for MIBC (n = 60). Participants indicated a strong preference for treatments that increased their life expectancy (p = <0.001), had a lower risk of long‐term complications (p = <0.001) and less changes to their body image (p = <0.001). Changes to sexual wellbeing (p = 0.09) or an increase in acute side effects (p = 0.99) did not influence preferences. Patients were willing to accept treatments with higher risk of long‐term complications to improve their life expectancy or body image. Conclusion When deciding on the type of treatment, increased life expectancy is the most important consideration for people with MIBC. The risk of long‐term complications and changes to overall body image as a result of treatment are also important. Our study also highlighted that patients are willing to accept a higher risk of long‐term complications to improve other treatment outcomes. Understanding patient preferences is important for shared decision‐making, which has an impact on quality of care for people living with MIBC. |
| format | Article |
| id | doaj-art-92fc6e5c6e7b49af9253d6f1255adf0e |
| institution | Kabale University |
| issn | 2688-4526 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | BJUI Compass |
| spelling | doaj-art-92fc6e5c6e7b49af9253d6f1255adf0e2025-01-22T02:21:03ZengWileyBJUI Compass2688-45262024-11-015111173118210.1002/bco2.443Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experimentLiam Mannion0Verity Watson1Vinod Mullassery2Rajesh Nair3Thomas Charlton4Margaret Northover5Deborah Enting6Mieke Van Hemelrijck7Muhammad Shamim Khan8Ramesh Thurairaja9Suzanne Amery10Kathryn Chatterton11Kate Smith12Simon Hughes13City University of London London UKUniversity of Aberdeen Aberdeen UKKing's College London London UKGuy's and St Thomas' NHS Foundation Trust London UKThe Royal Marsden NHS Foundation Trust London UKGuy's and St Thomas' NHS Foundation Trust London UKKing's College London London UKKing's College London London UKGuy's and St Thomas' NHS Foundation Trust London UKGuy's and St Thomas' NHS Foundation Trust London UKGuy's and St Thomas' NHS Foundation Trust London UKGuy's and St Thomas' NHS Foundation Trust London UKGuy's and St Thomas' NHS Foundation Trust London UKKing's College London London UKAbstract Background When faced with treatment options, patients are asked to participate in decision‐making. We sought to determine which treatment aspects matter most for individuals treated for muscle invasive bladder cancer (MIBC), with an aim to improve understanding of patient preferences and what trade‐offs patients are willing to accept. Our study consisted of a discrete choice experiment (DCE): a type of questionnaire used to elicit preferences in the absence of real‐world choice. Methods The DCE had five attributives, each with three levels. Participants were asked to complete a questionnaire in which they were asked to choose between two hypothetical MIBC treatments. The data were analysed using a conditional logit model, and preferences for, and trade‐offs between, attributes were estimated. Results We recruited patients with MIBC who had either already completed, were undergoing or had yet to commence radical treatment for MIBC (n = 60). Participants indicated a strong preference for treatments that increased their life expectancy (p = <0.001), had a lower risk of long‐term complications (p = <0.001) and less changes to their body image (p = <0.001). Changes to sexual wellbeing (p = 0.09) or an increase in acute side effects (p = 0.99) did not influence preferences. Patients were willing to accept treatments with higher risk of long‐term complications to improve their life expectancy or body image. Conclusion When deciding on the type of treatment, increased life expectancy is the most important consideration for people with MIBC. The risk of long‐term complications and changes to overall body image as a result of treatment are also important. Our study also highlighted that patients are willing to accept a higher risk of long‐term complications to improve other treatment outcomes. Understanding patient preferences is important for shared decision‐making, which has an impact on quality of care for people living with MIBC.https://doi.org/10.1002/bco2.443cancer treatment preferencesdiscrete choice experimentmuscle invasive bladder cancerpatient choice |
| spellingShingle | Liam Mannion Verity Watson Vinod Mullassery Rajesh Nair Thomas Charlton Margaret Northover Deborah Enting Mieke Van Hemelrijck Muhammad Shamim Khan Ramesh Thurairaja Suzanne Amery Kathryn Chatterton Kate Smith Simon Hughes Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment BJUI Compass cancer treatment preferences discrete choice experiment muscle invasive bladder cancer patient choice |
| title | Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment |
| title_full | Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment |
| title_fullStr | Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment |
| title_full_unstemmed | Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment |
| title_short | Treatment preferences of patients with muscle invasive bladder cancer: A discrete choice experiment |
| title_sort | treatment preferences of patients with muscle invasive bladder cancer a discrete choice experiment |
| topic | cancer treatment preferences discrete choice experiment muscle invasive bladder cancer patient choice |
| url | https://doi.org/10.1002/bco2.443 |
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