Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases

Introduction. Transplantation surgery teams often have to face complex cases. In certain circumstances, such as occlusion of the iliac vessels or prior pelvic surgery, heterotopic kidney transplantation may not be feasible and orthotopic kidney transplantation (OKT) could be a good alternative. Kidn...

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Main Authors: Alberto Artiles Medina, Victoria Gómez Dos Santos, Víctor Díez Nicolás, Vital Hevia Palacios, Mercedes Ruiz Hernández, Inés Laso García, Marina Mata Alcaraz, Cristina Galeano Álvarez, Miguel Ángel Jiménez Cidre, Fernando Arias Fúnez, Milagros Fernández Lucas, Francisco Javier Burgos Revilla
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2022/9299397
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author Alberto Artiles Medina
Victoria Gómez Dos Santos
Víctor Díez Nicolás
Vital Hevia Palacios
Mercedes Ruiz Hernández
Inés Laso García
Marina Mata Alcaraz
Cristina Galeano Álvarez
Miguel Ángel Jiménez Cidre
Fernando Arias Fúnez
Milagros Fernández Lucas
Francisco Javier Burgos Revilla
author_facet Alberto Artiles Medina
Victoria Gómez Dos Santos
Víctor Díez Nicolás
Vital Hevia Palacios
Mercedes Ruiz Hernández
Inés Laso García
Marina Mata Alcaraz
Cristina Galeano Álvarez
Miguel Ángel Jiménez Cidre
Fernando Arias Fúnez
Milagros Fernández Lucas
Francisco Javier Burgos Revilla
author_sort Alberto Artiles Medina
collection DOAJ
description Introduction. Transplantation surgery teams often have to face complex cases. In certain circumstances, such as occlusion of the iliac vessels or prior pelvic surgery, heterotopic kidney transplantation may not be feasible and orthotopic kidney transplantation (OKT) could be a good alternative. Kidney autotransplantation (KAT) has been described as a potential treatment for complex renovascular, ureteral, or neoplastic conditions. There are scarce data regarding the complications and outcomes of these procedures; therefore, we present our experience. Materials and Methods. We retrospectively analysed the medical records of both 21 patients who had received OKT and 19 patients who underwent KAT between 1993 and 2020. We collected demographic features and data regarding surgical technique, complications, and graft outcomes. Kidney graft survival was calculated using Kaplan–Meier survival analysis. Results. Regarding OKT, in 15 (71.43%) cases, it was the first kidney transplantation. The most common indication was the unsuitable iliac region due to vascular abnormalities (57.14%). The early postoperative complication rate was high (66.67%), with 23.81% of Clavien grade 3b complications. During the follow-up period (mean 5.76 -SD 6.15- years), we detected 9 (42.85%) graft losses. At 1 year, the survival rate was 84.9%. Concerning KAT, the most frequent indication was ureteral pathology (52.63%), followed by vascular lesions (42.11%). The overall early complication rate was 42.11%. During the follow-up period (mean of 4.47 years), 4 (15.79%) graft losses were reported. Conclusions. Although OKT and KAT have high complication rates, these techniques can be considered as two valuable approaches for complex cases, in the absence of other therapeutic options.
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spelling doaj-art-92e27d13ec0d44f2bc6a0d7b6a14372d2025-02-03T06:04:40ZengWileyAdvances in Urology1687-63772022-01-01202210.1155/2022/9299397Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex CasesAlberto Artiles Medina0Victoria Gómez Dos Santos1Víctor Díez Nicolás2Vital Hevia Palacios3Mercedes Ruiz Hernández4Inés Laso García5Marina Mata Alcaraz6Cristina Galeano Álvarez7Miguel Ángel Jiménez Cidre8Fernando Arias Fúnez9Milagros Fernández Lucas10Francisco Javier Burgos Revilla11Department of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of NephrologyDepartment of UrologyDepartment of UrologyDepartment of NephrologyDepartment of UrologyIntroduction. Transplantation surgery teams often have to face complex cases. In certain circumstances, such as occlusion of the iliac vessels or prior pelvic surgery, heterotopic kidney transplantation may not be feasible and orthotopic kidney transplantation (OKT) could be a good alternative. Kidney autotransplantation (KAT) has been described as a potential treatment for complex renovascular, ureteral, or neoplastic conditions. There are scarce data regarding the complications and outcomes of these procedures; therefore, we present our experience. Materials and Methods. We retrospectively analysed the medical records of both 21 patients who had received OKT and 19 patients who underwent KAT between 1993 and 2020. We collected demographic features and data regarding surgical technique, complications, and graft outcomes. Kidney graft survival was calculated using Kaplan–Meier survival analysis. Results. Regarding OKT, in 15 (71.43%) cases, it was the first kidney transplantation. The most common indication was the unsuitable iliac region due to vascular abnormalities (57.14%). The early postoperative complication rate was high (66.67%), with 23.81% of Clavien grade 3b complications. During the follow-up period (mean 5.76 -SD 6.15- years), we detected 9 (42.85%) graft losses. At 1 year, the survival rate was 84.9%. Concerning KAT, the most frequent indication was ureteral pathology (52.63%), followed by vascular lesions (42.11%). The overall early complication rate was 42.11%. During the follow-up period (mean of 4.47 years), 4 (15.79%) graft losses were reported. Conclusions. Although OKT and KAT have high complication rates, these techniques can be considered as two valuable approaches for complex cases, in the absence of other therapeutic options.http://dx.doi.org/10.1155/2022/9299397
spellingShingle Alberto Artiles Medina
Victoria Gómez Dos Santos
Víctor Díez Nicolás
Vital Hevia Palacios
Mercedes Ruiz Hernández
Inés Laso García
Marina Mata Alcaraz
Cristina Galeano Álvarez
Miguel Ángel Jiménez Cidre
Fernando Arias Fúnez
Milagros Fernández Lucas
Francisco Javier Burgos Revilla
Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases
Advances in Urology
title Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases
title_full Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases
title_fullStr Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases
title_full_unstemmed Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases
title_short Kidney Autotransplantation and Orthotopic Kidney Transplantation: Two Different Approaches for Complex Cases
title_sort kidney autotransplantation and orthotopic kidney transplantation two different approaches for complex cases
url http://dx.doi.org/10.1155/2022/9299397
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