Convergent evolution of oxidized sugar metabolism in commensal and pathogenic microbes in the inflamed gut

Abstract Inflammation-associated perturbations of the gut microbiome are well characterized, but poorly understood. Here, we demonstrate that disparate taxa recapitulate the metabolism of the oxidized sugars glucarate and galactarate, utilizing enzymatically divergent, yet functionally equivalent, g...

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Bibliographic Details
Main Authors: Sophia Levy, Angela K. Jiang, Maggie R. Grant, Gabriela Arp, Glory Minabou Ndjite, Xiaofang Jiang, Brantley Hall
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56332-9
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