Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens

The utilization of mangosteen biomass not only solves environmental problems but also raises the value of agricultural waste. The current study aimed to evaluate the potential of mangosteen pericarp extract (MPE) for enhancing the immunity and productivity of Thai native crossbred chickens on-farm....

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Main Authors: Phruedrada Kaewtui, Chompunut Lumsangkul, Apinya Satsook, Korawan Sringarm, Chaiwat Arjin, Wanaporn Tapingkae, Pimporn Khamtavee, Orranee Srinual, Montri Punyatong, Kiattisak Huanhong, Peerawit Chongrattanameteekul, Natpasit Rattaworapanit, Thanawut Mangkang, Raktham Mektrirat
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/14/11/1481
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author Phruedrada Kaewtui
Chompunut Lumsangkul
Apinya Satsook
Korawan Sringarm
Chaiwat Arjin
Wanaporn Tapingkae
Pimporn Khamtavee
Orranee Srinual
Montri Punyatong
Kiattisak Huanhong
Peerawit Chongrattanameteekul
Natpasit Rattaworapanit
Thanawut Mangkang
Raktham Mektrirat
author_facet Phruedrada Kaewtui
Chompunut Lumsangkul
Apinya Satsook
Korawan Sringarm
Chaiwat Arjin
Wanaporn Tapingkae
Pimporn Khamtavee
Orranee Srinual
Montri Punyatong
Kiattisak Huanhong
Peerawit Chongrattanameteekul
Natpasit Rattaworapanit
Thanawut Mangkang
Raktham Mektrirat
author_sort Phruedrada Kaewtui
collection DOAJ
description The utilization of mangosteen biomass not only solves environmental problems but also raises the value of agricultural waste. The current study aimed to evaluate the potential of mangosteen pericarp extract (MPE) for enhancing the immunity and productivity of Thai native crossbred chickens on-farm. A total of 180 three-week-old chickens were divided into negative control and supplemented groups, with 1000 mg MPE/kg of diet. The safety of MPE was further confirmed by the absence of noticeable differences in mortality and biochemical parameters during the entire study period. The MPE-supplemented group displayed significant differences in the relative transcription levels of IL-10 compared to the basal diet group (<i>p</i> ≤ 0.01). Preslaughter body weight, average daily gain, and carcass weight in the MPE-supplemented group were higher than those in the basal diet group (<i>p</i> ≤ 0.05). Furthermore, MPE supplementation improved meat quality by enhancing the nutritional composition of protein and fat (<i>p</i> ≤ 0.05), as well as improving water-holding capacity, lowering boiling, and lowering grilling losses (<i>p</i> ≤ 0.01). These findings indicate that MPE can be an effective supplement for enhancing flock immunity, growth performance, and meat quality in poultry. This contributes to more sustainable agriculture and food security within agroecosystems.
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spelling doaj-art-92a244c6e9f7461b9f6e07cc18ab47002025-08-20T02:48:05ZengMDPI AGLife2075-17292024-11-011411148110.3390/life14111481Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred ChickensPhruedrada Kaewtui0Chompunut Lumsangkul1Apinya Satsook2Korawan Sringarm3Chaiwat Arjin4Wanaporn Tapingkae5Pimporn Khamtavee6Orranee Srinual7Montri Punyatong8Kiattisak Huanhong9Peerawit Chongrattanameteekul10Natpasit Rattaworapanit11Thanawut Mangkang12Raktham Mektrirat13Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, ThailandVeterinary Academic Office, Faculty of Veterinary Medicine, Chiang Mai University, Muang, Chiang Mai 50100, ThailandVeterinary Academic Office, Faculty of Veterinary Medicine, Chiang Mai University, Muang, Chiang Mai 50100, ThailandVeterinary Academic Office, Faculty of Veterinary Medicine, Chiang Mai University, Muang, Chiang Mai 50100, ThailandVeterinary Academic Office, Faculty of Veterinary Medicine, Chiang Mai University, Muang, Chiang Mai 50100, ThailandThe utilization of mangosteen biomass not only solves environmental problems but also raises the value of agricultural waste. The current study aimed to evaluate the potential of mangosteen pericarp extract (MPE) for enhancing the immunity and productivity of Thai native crossbred chickens on-farm. A total of 180 three-week-old chickens were divided into negative control and supplemented groups, with 1000 mg MPE/kg of diet. The safety of MPE was further confirmed by the absence of noticeable differences in mortality and biochemical parameters during the entire study period. The MPE-supplemented group displayed significant differences in the relative transcription levels of IL-10 compared to the basal diet group (<i>p</i> ≤ 0.01). Preslaughter body weight, average daily gain, and carcass weight in the MPE-supplemented group were higher than those in the basal diet group (<i>p</i> ≤ 0.05). Furthermore, MPE supplementation improved meat quality by enhancing the nutritional composition of protein and fat (<i>p</i> ≤ 0.05), as well as improving water-holding capacity, lowering boiling, and lowering grilling losses (<i>p</i> ≤ 0.01). These findings indicate that MPE can be an effective supplement for enhancing flock immunity, growth performance, and meat quality in poultry. This contributes to more sustainable agriculture and food security within agroecosystems.https://www.mdpi.com/2075-1729/14/11/1481feed additivegrowth performancemeat qualitymangosteenpoultrysustainability
spellingShingle Phruedrada Kaewtui
Chompunut Lumsangkul
Apinya Satsook
Korawan Sringarm
Chaiwat Arjin
Wanaporn Tapingkae
Pimporn Khamtavee
Orranee Srinual
Montri Punyatong
Kiattisak Huanhong
Peerawit Chongrattanameteekul
Natpasit Rattaworapanit
Thanawut Mangkang
Raktham Mektrirat
Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens
Life
feed additive
growth performance
meat quality
mangosteen
poultry
sustainability
title Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens
title_full Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens
title_fullStr Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens
title_full_unstemmed Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens
title_short Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens
title_sort initial evaluation of safety and immunomodulatory potential of dietary supplementation with mangosteen pericarp extract for sustainable meat production in native crossbred chickens
topic feed additive
growth performance
meat quality
mangosteen
poultry
sustainability
url https://www.mdpi.com/2075-1729/14/11/1481
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