Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction

To our knowledge, we are reporting the first case of a 59-year-old man who developed recurrent CME with three separate trials of three different prostaglandin class drugs following uncomplicated phacoemulsification with intraocular lens implantation. Despite multiple reports of individual prostaglan...

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Main Authors: Negin Agange, Sameh Mosaed
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2010/690707
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author Negin Agange
Sameh Mosaed
author_facet Negin Agange
Sameh Mosaed
author_sort Negin Agange
collection DOAJ
description To our knowledge, we are reporting the first case of a 59-year-old man who developed recurrent CME with three separate trials of three different prostaglandin class drugs following uncomplicated phacoemulsification with intraocular lens implantation. Despite multiple reports of individual prostaglandin (PG) analogues being suggested as the cause of CME, there are no recommendations regarding withholding these medications in the perioperative period. Our patient first developed CME OD 4-months post uncomplicated cataract extraction. XALATAN (Latanoprost) had been restarted after surgery and discontinued at onset of CME. While off XALATAN (Latanoprost), the patient's CME resolved, but his IOP rose. The patient was started on LUMIGAN (Bimatoprost) to control the IOP, but within weeks his CME recurred. The patient's CME was again treated and his IOP remained acceptable, but then progressively increased. TRAVATAN (Travoprost) was attempted, but he presented with a third round of CME. Definitive conclusions about causal relationships cannot be made without well-designed, prospective clinical trials addressing this issue.
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spelling doaj-art-9298dcd7d2e04dd2a8f41fccacf578582025-02-03T01:31:40ZengWileyJournal of Ophthalmology2090-004X2090-00582010-01-01201010.1155/2010/690707690707Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract ExtractionNegin Agange0Sameh Mosaed1Department of Ophthalmology, University of California, Irvine, CA 92697, USADepartment of Ophthalmology, University of California, Irvine, CA 92697, USATo our knowledge, we are reporting the first case of a 59-year-old man who developed recurrent CME with three separate trials of three different prostaglandin class drugs following uncomplicated phacoemulsification with intraocular lens implantation. Despite multiple reports of individual prostaglandin (PG) analogues being suggested as the cause of CME, there are no recommendations regarding withholding these medications in the perioperative period. Our patient first developed CME OD 4-months post uncomplicated cataract extraction. XALATAN (Latanoprost) had been restarted after surgery and discontinued at onset of CME. While off XALATAN (Latanoprost), the patient's CME resolved, but his IOP rose. The patient was started on LUMIGAN (Bimatoprost) to control the IOP, but within weeks his CME recurred. The patient's CME was again treated and his IOP remained acceptable, but then progressively increased. TRAVATAN (Travoprost) was attempted, but he presented with a third round of CME. Definitive conclusions about causal relationships cannot be made without well-designed, prospective clinical trials addressing this issue.http://dx.doi.org/10.1155/2010/690707
spellingShingle Negin Agange
Sameh Mosaed
Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction
Journal of Ophthalmology
title Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction
title_full Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction
title_fullStr Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction
title_full_unstemmed Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction
title_short Prostaglandin-Induced Cystoid Macular Edema Following Routine Cataract Extraction
title_sort prostaglandin induced cystoid macular edema following routine cataract extraction
url http://dx.doi.org/10.1155/2010/690707
work_keys_str_mv AT neginagange prostaglandininducedcystoidmacularedemafollowingroutinecataractextraction
AT samehmosaed prostaglandininducedcystoidmacularedemafollowingroutinecataractextraction