Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature

Bortezomib, a proteasome inhibitor, is an established therapy against multiple myeloma. Bortezomib-induced lung injury, although not appreciated during the introductory time of the medication, has now been highlighted in multiple case reports. The objective of this study is to report a case of borte...

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Main Authors: Prakash Kharel, Deekchha Uprety, Abhinav B. Chandra, Yirui Hu, Anuradha Avinash Belur, Ajay Dhakal
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2018/2913124
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author Prakash Kharel
Deekchha Uprety
Abhinav B. Chandra
Yirui Hu
Anuradha Avinash Belur
Ajay Dhakal
author_facet Prakash Kharel
Deekchha Uprety
Abhinav B. Chandra
Yirui Hu
Anuradha Avinash Belur
Ajay Dhakal
author_sort Prakash Kharel
collection DOAJ
description Bortezomib, a proteasome inhibitor, is an established therapy against multiple myeloma. Bortezomib-induced lung injury, although not appreciated during the introductory time of the medication, has now been highlighted in multiple case reports. The objective of this study is to report a case of bortezomib-induced lung injury, review current literature, and perform exploratory analysis.
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institution Kabale University
issn 1687-9627
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publishDate 2018-01-01
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series Case Reports in Medicine
spelling doaj-art-92857cec6a3a47e1930e6e4204ce54812025-02-03T01:12:52ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/29131242913124Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of LiteraturePrakash Kharel0Deekchha Uprety1Abhinav B. Chandra2Yirui Hu3Anuradha Avinash Belur4Ajay Dhakal5Department of Hospital Medicine, Geisinger Medical Center, 100 N Academy Ave., Danville, PA 17821, USARenal Division, Brigham and Women’s Hospital, Boston, MA, USAYuma Regional Medical Center, Yuma, AZ, USACenter for Health Research, Geisinger Medical Center, 100 N Academy Ave., Danville, PA 17821, USAMulti Care Regional Cancer Center, Auburn, WA, USADepartment of Medicine, Wilmot Cancer Institute, University of Rochester, Rochester, NY, USABortezomib, a proteasome inhibitor, is an established therapy against multiple myeloma. Bortezomib-induced lung injury, although not appreciated during the introductory time of the medication, has now been highlighted in multiple case reports. The objective of this study is to report a case of bortezomib-induced lung injury, review current literature, and perform exploratory analysis.http://dx.doi.org/10.1155/2018/2913124
spellingShingle Prakash Kharel
Deekchha Uprety
Abhinav B. Chandra
Yirui Hu
Anuradha Avinash Belur
Ajay Dhakal
Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature
Case Reports in Medicine
title Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature
title_full Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature
title_fullStr Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature
title_full_unstemmed Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature
title_short Bortezomib-Induced Pulmonary Toxicity: A Case Report and Review of Literature
title_sort bortezomib induced pulmonary toxicity a case report and review of literature
url http://dx.doi.org/10.1155/2018/2913124
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