Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans

Moderate intake of whole grains and non-soy legumes can improve glucose and lipid metabolism, but excessive intake may have an adverse effect. Due to the lack of corresponding conversion relationships, the intake of whole grains and non-soy legumes in mouse feed cannot directly serve as a reference...

Full description

Saved in:
Bibliographic Details
Main Author: ZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun
Format: Article
Language:English
Published: China Food Publishing Company 2025-01-01
Series:Shipin Kexue
Subjects:
Online Access:https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-2-014.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832539763727400960
author ZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun
author_facet ZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun
author_sort ZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun
collection DOAJ
description Moderate intake of whole grains and non-soy legumes can improve glucose and lipid metabolism, but excessive intake may have an adverse effect. Due to the lack of corresponding conversion relationships, the intake of whole grains and non-soy legumes in mouse feed cannot directly serve as a reference for human intake. This paper introduces the addition levels of common whole grains and non-soy legumes in mouse feed and explores their relationship with the recommended dietary intakes (RDI) of common whole grains and non-soy legumes in humans using various methods, including equivalent coefficient, surface area ratio, body shape coefficient, food density, body surface area index, energy conversion, and nutrient conversion methods. The results indicate that the RDI of 50–150 g of whole grains and non-soy legumes in humans could be equivalently converted into addition of 5%–50% whole grains and beans in the feed of mice with a 3 g daily feed intake. Dietary addition of whole grains and non-soy legumes exceeding 50% might place mice at risk for overconsumption. This study provides an important reference for establishing the conversion relationship between the amounts of whole grains and non-soy legumes added to mouse feed and the RDI of whole grains and non-soy legumes in humans.
format Article
id doaj-art-925f60293d364fe297cb511346d092ec
institution Kabale University
issn 1002-6630
language English
publishDate 2025-01-01
publisher China Food Publishing Company
record_format Article
series Shipin Kexue
spelling doaj-art-925f60293d364fe297cb511346d092ec2025-02-05T09:08:22ZengChina Food Publishing CompanyShipin Kexue1002-66302025-01-0146211812510.7506/spkx1002-6630-20240621-148Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and HumansZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun0(National Center of Technology Innovation (Deep Processing of Highland Barley) in Food Industry, National Research Center for Grain and Oil Standards Testing, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)Moderate intake of whole grains and non-soy legumes can improve glucose and lipid metabolism, but excessive intake may have an adverse effect. Due to the lack of corresponding conversion relationships, the intake of whole grains and non-soy legumes in mouse feed cannot directly serve as a reference for human intake. This paper introduces the addition levels of common whole grains and non-soy legumes in mouse feed and explores their relationship with the recommended dietary intakes (RDI) of common whole grains and non-soy legumes in humans using various methods, including equivalent coefficient, surface area ratio, body shape coefficient, food density, body surface area index, energy conversion, and nutrient conversion methods. The results indicate that the RDI of 50–150 g of whole grains and non-soy legumes in humans could be equivalently converted into addition of 5%–50% whole grains and beans in the feed of mice with a 3 g daily feed intake. Dietary addition of whole grains and non-soy legumes exceeding 50% might place mice at risk for overconsumption. This study provides an important reference for establishing the conversion relationship between the amounts of whole grains and non-soy legumes added to mouse feed and the RDI of whole grains and non-soy legumes in humans.https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-2-014.pdfdose conversion; whole grains; non-soy legumes; body surface area
spellingShingle ZHI Li, ZHU Yiqing, ZHAO Liangxing, CHEN Rui, ZHAO Qingyu, WANG Chao, XUE Yong, SHEN Qun
Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
Shipin Kexue
dose conversion; whole grains; non-soy legumes; body surface area
title Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
title_full Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
title_fullStr Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
title_full_unstemmed Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
title_short Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
title_sort dietary dose conversion of whole grains and non soy legumes between mice and humans
topic dose conversion; whole grains; non-soy legumes; body surface area
url https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-2-014.pdf
work_keys_str_mv AT zhilizhuyiqingzhaoliangxingchenruizhaoqingyuwangchaoxueyongshenqun dietarydoseconversionofwholegrainsandnonsoylegumesbetweenmiceandhumans