The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging
Background. It is expected that a combination of amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as laser-assisted drug delivery (LADD) will provide better effects in photoaging treatment as the combination reaches the target. This promises an option...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/1584541 |
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| author | Rahmadewi Rahmadewi Retha Retha Dyah Ayu Pitasari Vidyani Adiningtyas Kusumastanto Agatha Anindita Ayu Ardhaninggar Irmadita Citrashanty Maylita Sari Menul Ayu Umborowati Cita Rosita Sigit Prakoeswa |
| author_facet | Rahmadewi Rahmadewi Retha Retha Dyah Ayu Pitasari Vidyani Adiningtyas Kusumastanto Agatha Anindita Ayu Ardhaninggar Irmadita Citrashanty Maylita Sari Menul Ayu Umborowati Cita Rosita Sigit Prakoeswa |
| author_sort | Rahmadewi Rahmadewi |
| collection | DOAJ |
| description | Background. It is expected that a combination of amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as laser-assisted drug delivery (LADD) will provide better effects in photoaging treatment as the combination reaches the target. This promises an option for photoaging therapy in the future. Materials and Methods. Sixty women with photoaged skins were involved in this experimental study. They were then divided into two groups. The treatment group received a topical combination of AMSC-MP and vitamin E, and the control group received AMSC-MP alone after fractional CO2 laser. The treatment was repeated three times. Result. The Janus assessment results showed a significant difference in pores in the third observation, and the average pore improvements in the treatment group were better than the control group. Wrinkle, UV spot, and polar spot did not show any significant difference. Conclusion. A combination of the amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as LADD only improves pores in photoaged skins. |
| format | Article |
| id | doaj-art-924a5ec146ae4b9bb85831ffe3e0505d |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-924a5ec146ae4b9bb85831ffe3e0505d2025-02-03T05:44:12ZengWileyDermatology Research and Practice1687-61051687-61132020-01-01202010.1155/2020/15845411584541The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in PhotoagingRahmadewi Rahmadewi0Retha Retha1Dyah Ayu Pitasari2Vidyani Adiningtyas Kusumastanto3Agatha Anindita Ayu Ardhaninggar4Irmadita Citrashanty5Maylita Sari6Menul Ayu Umborowati7Cita Rosita Sigit Prakoeswa8Dermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaDermatology and Venereology Department, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya, IndonesiaBackground. It is expected that a combination of amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as laser-assisted drug delivery (LADD) will provide better effects in photoaging treatment as the combination reaches the target. This promises an option for photoaging therapy in the future. Materials and Methods. Sixty women with photoaged skins were involved in this experimental study. They were then divided into two groups. The treatment group received a topical combination of AMSC-MP and vitamin E, and the control group received AMSC-MP alone after fractional CO2 laser. The treatment was repeated three times. Result. The Janus assessment results showed a significant difference in pores in the third observation, and the average pore improvements in the treatment group were better than the control group. Wrinkle, UV spot, and polar spot did not show any significant difference. Conclusion. A combination of the amniotic membrane stem cell metabolite product (AMSC-MP) and vitamin E after fractional CO2 laser as LADD only improves pores in photoaged skins.http://dx.doi.org/10.1155/2020/1584541 |
| spellingShingle | Rahmadewi Rahmadewi Retha Retha Dyah Ayu Pitasari Vidyani Adiningtyas Kusumastanto Agatha Anindita Ayu Ardhaninggar Irmadita Citrashanty Maylita Sari Menul Ayu Umborowati Cita Rosita Sigit Prakoeswa The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging Dermatology Research and Practice |
| title | The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging |
| title_full | The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging |
| title_fullStr | The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging |
| title_full_unstemmed | The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging |
| title_short | The Efficacy of Amniotic Membrane Stem Cell (AMSC) Metabolite Product and Vitamin E for Wrinkles, Spots, and Pores in Photoaging |
| title_sort | efficacy of amniotic membrane stem cell amsc metabolite product and vitamin e for wrinkles spots and pores in photoaging |
| url | http://dx.doi.org/10.1155/2020/1584541 |
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