Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis

Renal complications from snakebite result in high mortality and morbidity. Acute kidney injury (AKI) occurs in 5–30% of cases. Renal manifestation could include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasculitis. We present a case of thrombotic micr...

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Main Authors: Ying Mao Gn, Arvind Ponnusamy, Vikram Thimma
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2017/1348749
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author Ying Mao Gn
Arvind Ponnusamy
Vikram Thimma
author_facet Ying Mao Gn
Arvind Ponnusamy
Vikram Thimma
author_sort Ying Mao Gn
collection DOAJ
description Renal complications from snakebite result in high mortality and morbidity. Acute kidney injury (AKI) occurs in 5–30% of cases. Renal manifestation could include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasculitis. We present a case of thrombotic microangiopathy (TMA) resulting in renal cortical necrosis. Renal biopsy showed fibrin thrombi in glomeruli and arterioles with cortical necrosis. Our patient progressed to end-stage renal disease.
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spelling doaj-art-924a1368c4e94cfeb400fc4df252e1cc2025-02-03T01:32:17ZengWileyCase Reports in Nephrology2090-66412090-665X2017-01-01201710.1155/2017/13487491348749Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical NecrosisYing Mao Gn0Arvind Ponnusamy1Vikram Thimma2Renal Department, Royal Preston Hospital, Preston, UKRenal Department, Royal Preston Hospital, Preston, UKRenal Department, Velammal Medical College Hospital, Madurai, IndiaRenal complications from snakebite result in high mortality and morbidity. Acute kidney injury (AKI) occurs in 5–30% of cases. Renal manifestation could include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasculitis. We present a case of thrombotic microangiopathy (TMA) resulting in renal cortical necrosis. Renal biopsy showed fibrin thrombi in glomeruli and arterioles with cortical necrosis. Our patient progressed to end-stage renal disease.http://dx.doi.org/10.1155/2017/1348749
spellingShingle Ying Mao Gn
Arvind Ponnusamy
Vikram Thimma
Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis
Case Reports in Nephrology
title Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis
title_full Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis
title_fullStr Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis
title_full_unstemmed Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis
title_short Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis
title_sort snakebite induced thrombotic microangiopathy leading to renal cortical necrosis
url http://dx.doi.org/10.1155/2017/1348749
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AT arvindponnusamy snakebiteinducedthromboticmicroangiopathyleadingtorenalcorticalnecrosis
AT vikramthimma snakebiteinducedthromboticmicroangiopathyleadingtorenalcorticalnecrosis