Large language models provide discordant information compared to ophthalmology guidelines

Large language models provide discordant information compared to ophthalmology guidelines

Abstract To evaluate the agreement of LLMs with the Preferred Practice Patterns® (PPP) guidelines developed by the American Academy of Ophthalmology (AAO). Open questions based on the AAO PPP were submitted to five LLMs: GPT-o1 and GPT-4o by OpenAI, Claude 3.5 Sonnet by Anthropic, Gemini 1.5 Pro by...

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Bibliographic Details
Main Authors: Andrea Taloni, Antonia Carmen Sangregorio, Giuseppe Alessio, Maria Angela Romeo, Giulia Coco, Linda Marie Louise Busin, Andrea Sollazzo, Vincenzo Scorcia, Giuseppe Giannaccare
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Large language model
Artificial intelligence
Guidelines
Preferred practice patterns
American Academy of Ophthalmology
AAO
Online Access:https://doi.org/10.1038/s41598-025-06404-z
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