Evaluating the Impact of Hepatic or Renal Impairment on Tanimilast (CHF6001) Pharmacokinetics: Two Open‐Label, Parallel‐Group, Single‐Center Studies

ABSTRACT Tanimilast is an inhaled phosphodiesterase‐4 inhibitor in development for chronic obstructive pulmonary disease and asthma. We conducted two studies to evaluate tanimilast pharmacokinetics, one in subjects with mild, moderate, or severe hepatic impairment and matched healthy controls, and o...

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Main Authors: Annalisa Piccinno, Maria Gloria Pittelli, Deborah Balzano, Elisa Rizzo, Pooja Bellatti, Chiara Rostello, Aida Emirova
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Clinical and Translational Science
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Online Access:https://doi.org/10.1111/cts.70261
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