Berberine alleviates chronic pain-induced anxiety-like behaviors by inhibiting the activation of VLT-projecting cACC (Cg2) neurons
Abstract Chronic pain is often accompanied by anxiety, and gradually increasing anxiety makes the pain itself more protracted. Berberine has been found to be able to cross the blood–brain barrier to treat psychiatric disorders, but its neurocirculatory mechanisms remain unclear. Here, we found that...
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| Main Authors: | Min He, Ye-Xiang Chen, Pei-Pei Feng, Jie Chen, Chi Xu, Shu-Ting Zhou, Bo-Yu Liu, Xiao-Fen He, Xiao-Mei Shao, Jian-Qiao Fang, Zui Shen, Jing-Gen Liu |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-024-07372-2 |
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