A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment
Bier's spots are rare angiospastic macules often associated with physiologic vasoconstriction. This case report describes a 35-year-old man with chronic myeloid leukemia treated with nilotinib who developed Bier's spots, a previously unreported adverse effect of the drug. The patient pres...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2025-01-01
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| Series: | Dermatology Reports |
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| Online Access: | https://www.pagepress.org/journals/dr/article/view/10160 |
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| author | Ahmed Alsaati Turki Hakami Sultan Bajawi Gamil Mohammed Nouf Bajawi Nadya Al-Faraidy |
| author_facet | Ahmed Alsaati Turki Hakami Sultan Bajawi Gamil Mohammed Nouf Bajawi Nadya Al-Faraidy |
| author_sort | Ahmed Alsaati |
| collection | DOAJ |
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Bier's spots are rare angiospastic macules often associated with physiologic vasoconstriction. This case report describes a 35-year-old man with chronic myeloid leukemia treated with nilotinib who developed Bier's spots, a previously unreported adverse effect of the drug. The patient presented with asymptomatic hypopigmented macules on the hands and legs that appeared during venous stasis and resolved with elevation. This case emphasizes the need to recognize potential vascular side effects of tyrosine kinase inhibitors and highlights Bier's spots as a benign but remarkable manifestation in patients undergoing nilotinib therapy.
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| format | Article |
| id | doaj-art-9219fc900e0f438cae294a3c6e7b156f |
| institution | Kabale University |
| issn | 2036-7392 2036-7406 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj-art-9219fc900e0f438cae294a3c6e7b156f2025-02-01T01:44:20ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062025-01-0110.4081/dr.2025.10160A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatmentAhmed Alsaati0Turki Hakami1Sultan Bajawi2Gamil Mohammed3Nouf Bajawi4Nadya Al-Faraidy5Department of Dermatology, Dammam Medical Complex, Ministry of Health, DammamDepartment of Dermatology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, KhobarDepartment of Dermatology, King Fahad Specialist Hospital, Ministry of Health, DammamDepartment of Dermatology, King Fahad Specialist Hospital, Ministry of Health, DammamJazan Health Cluster, Ministry of Health, JazanDepartment of Dermatology, King Fahad Specialist Hospital, Ministry of Health, Dammam Bier's spots are rare angiospastic macules often associated with physiologic vasoconstriction. This case report describes a 35-year-old man with chronic myeloid leukemia treated with nilotinib who developed Bier's spots, a previously unreported adverse effect of the drug. The patient presented with asymptomatic hypopigmented macules on the hands and legs that appeared during venous stasis and resolved with elevation. This case emphasizes the need to recognize potential vascular side effects of tyrosine kinase inhibitors and highlights Bier's spots as a benign but remarkable manifestation in patients undergoing nilotinib therapy. https://www.pagepress.org/journals/dr/article/view/10160Bier’s spotscase reportchronic myeloid leukemianilotinibvascular manifestation |
| spellingShingle | Ahmed Alsaati Turki Hakami Sultan Bajawi Gamil Mohammed Nouf Bajawi Nadya Al-Faraidy A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment Dermatology Reports Bier’s spots case report chronic myeloid leukemia nilotinib vascular manifestation |
| title | A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment |
| title_full | A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment |
| title_fullStr | A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment |
| title_full_unstemmed | A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment |
| title_short | A rare vascular manifestation in chronic myeloid leukemia: a case report and literature review of Bier's spot development during nilotinib treatment |
| title_sort | rare vascular manifestation in chronic myeloid leukemia a case report and literature review of bier s spot development during nilotinib treatment |
| topic | Bier’s spots case report chronic myeloid leukemia nilotinib vascular manifestation |
| url | https://www.pagepress.org/journals/dr/article/view/10160 |
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