Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota

Diet therapy is often the first-line approach in prevention and management of type 2 diabetes mellitus (T2DM). Adoption of low glycaemic index (GI) diet one of the recent dietary strategies to modulate glycaemic response in individuals with T2DM. Generally, diet has strong influence on the gut micro...

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Main Authors: Hanusha Durganaudu, Thubasni Kunasegaran, Amutha Ramadas
Format: Article
Language:English
Published: HH Publisher 2020-05-01
Series:Progress in Microbes and Molecular Biology
Online Access:https://journals.hh-publisher.com/index.php/pmmb/article/view/260
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author Hanusha Durganaudu
Thubasni Kunasegaran
Amutha Ramadas
author_facet Hanusha Durganaudu
Thubasni Kunasegaran
Amutha Ramadas
author_sort Hanusha Durganaudu
collection DOAJ
description Diet therapy is often the first-line approach in prevention and management of type 2 diabetes mellitus (T2DM). Adoption of low glycaemic index (GI) diet one of the recent dietary strategies to modulate glycaemic response in individuals with T2DM. Generally, diet has strong influence on the gut microbiota, which recently have been found to be associated with insulin resistance and the inflammatory response in diabetes. The possible modulation of the gut microbiota with dietary intervention is a topic of emerging interest, with limited evidence among T2DM population. In this review, we have narrated the available evidence and discussed the current knowledge about diet manipulation associated with dietary GI in order to shape the gut microbiota. As a conclusion, we have pointed out several key research directions that may have helpful impact on diet interventions with modulation of gut microbiota on the pathogenesis and therapeutic implications in T2DM.
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institution Kabale University
issn 2637-1049
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series Progress in Microbes and Molecular Biology
spelling doaj-art-9219980c5ff14ef7b94633a1ce5303602025-02-04T08:37:05ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492020-05-013110.36877/pmmb.a0000082Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut MicrobiotaHanusha DurganauduThubasni KunasegaranAmutha RamadasDiet therapy is often the first-line approach in prevention and management of type 2 diabetes mellitus (T2DM). Adoption of low glycaemic index (GI) diet one of the recent dietary strategies to modulate glycaemic response in individuals with T2DM. Generally, diet has strong influence on the gut microbiota, which recently have been found to be associated with insulin resistance and the inflammatory response in diabetes. The possible modulation of the gut microbiota with dietary intervention is a topic of emerging interest, with limited evidence among T2DM population. In this review, we have narrated the available evidence and discussed the current knowledge about diet manipulation associated with dietary GI in order to shape the gut microbiota. As a conclusion, we have pointed out several key research directions that may have helpful impact on diet interventions with modulation of gut microbiota on the pathogenesis and therapeutic implications in T2DM.https://journals.hh-publisher.com/index.php/pmmb/article/view/260
spellingShingle Hanusha Durganaudu
Thubasni Kunasegaran
Amutha Ramadas
Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
Progress in Microbes and Molecular Biology
title Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
title_full Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
title_fullStr Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
title_full_unstemmed Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
title_short Dietary Glycaemic Index and Type 2 Diabetes Mellitus: Potential Modulation of Gut Microbiota
title_sort dietary glycaemic index and type 2 diabetes mellitus potential modulation of gut microbiota
url https://journals.hh-publisher.com/index.php/pmmb/article/view/260
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AT amutharamadas dietaryglycaemicindexandtype2diabetesmellituspotentialmodulationofgutmicrobiota