Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles

Physical activity could lead to dehydration and post-exercise proteinuria. In several animal studies, it has been noticed that aronia juice consumption shows favorable effects on the kidney function. Therefore, the primary aim of this study was to examine the influence of acute aronia juice suppleme...

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Main Authors: Marija Takić, Tamara Uzelac, Nevena Vidovic, Vuk Stevanovic, Ana Pantovic, Marija Glibetic, Vesna Jovanovic
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/91/1/196
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author Marija Takić
Tamara Uzelac
Nevena Vidovic
Vuk Stevanovic
Ana Pantovic
Marija Glibetic
Vesna Jovanovic
author_facet Marija Takić
Tamara Uzelac
Nevena Vidovic
Vuk Stevanovic
Ana Pantovic
Marija Glibetic
Vesna Jovanovic
author_sort Marija Takić
collection DOAJ
description Physical activity could lead to dehydration and post-exercise proteinuria. In several animal studies, it has been noticed that aronia juice consumption shows favorable effects on the kidney function. Therefore, the primary aim of this study was to examine the influence of acute aronia juice supplementation before simulated half-marathon races on serum protein profiles that reflect both changes induced by dehydration and proteinuria in ten recreational runners. The serum protein profiles were determined before (T0), 15 min (T1), 1 h (T2), and 24 h after the race (T3), and were presented as a percentage abundance of HSA and non-albumin fractions (γ, β2, α1, and α2) obtained through the densitometric analysis of gels after the separation of serum proteins via native electrophoresis. Before the first race, our recreational runners had decreased percentages of α1- and α2-globulins and increased percentages of γ-globulins compared to the literature values for healthy subjects. At time points T2 and T3, after simulation of the half-marathon races, the significant increase (<i>p</i> < 0.05) in γ fraction percentages was noticed after the placebo, but not the acute aronia juice treatment. According to the obtained results, long-term physical activity in recreational runners induces changes in serum protein profiles, probably due to the protein loss of low-weight proteins after exercise. At the same time, this study has shown that the acute consumption of aronia juice before intensive physical activity could exert a beneficial effect on post-exercise proteinuria.
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spelling doaj-art-91efb7a8c3f8491b85eb6b680031a6be2025-08-20T03:43:54ZengMDPI AGProceedings2504-39002024-02-0191119610.3390/proceedings2023091196Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein ProfilesMarija Takić0Tamara Uzelac1Nevena Vidovic2Vuk Stevanovic3Ana Pantovic4Marija Glibetic5Vesna Jovanovic6Institute for Medical Research, National Institute of Republic of Serbia, Center of Research Excellence in Nutrition and Metabolism, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Chemistry, Department of Biochemistry and Centre of Excellence for Molecular Food Sciences, University of Belgrade, 11000 Belgrade, SerbiaInstitute for Medical Research, National Institute of Republic of Serbia, Center of Research Excellence in Nutrition and Metabolism, University of Belgrade, 11000 Belgrade, SerbiaInstitute for Medical Research, National Institute of Republic of Serbia, Center of Research Excellence in Nutrition and Metabolism, University of Belgrade, 11000 Belgrade, SerbiaInstitute for Medical Research, National Institute of Republic of Serbia, Center of Research Excellence in Nutrition and Metabolism, University of Belgrade, 11000 Belgrade, SerbiaInstitute for Medical Research, National Institute of Republic of Serbia, Center of Research Excellence in Nutrition and Metabolism, University of Belgrade, 11000 Belgrade, SerbiaFaculty of Chemistry, Department of Biochemistry and Centre of Excellence for Molecular Food Sciences, University of Belgrade, 11000 Belgrade, SerbiaPhysical activity could lead to dehydration and post-exercise proteinuria. In several animal studies, it has been noticed that aronia juice consumption shows favorable effects on the kidney function. Therefore, the primary aim of this study was to examine the influence of acute aronia juice supplementation before simulated half-marathon races on serum protein profiles that reflect both changes induced by dehydration and proteinuria in ten recreational runners. The serum protein profiles were determined before (T0), 15 min (T1), 1 h (T2), and 24 h after the race (T3), and were presented as a percentage abundance of HSA and non-albumin fractions (γ, β2, α1, and α2) obtained through the densitometric analysis of gels after the separation of serum proteins via native electrophoresis. Before the first race, our recreational runners had decreased percentages of α1- and α2-globulins and increased percentages of γ-globulins compared to the literature values for healthy subjects. At time points T2 and T3, after simulation of the half-marathon races, the significant increase (<i>p</i> < 0.05) in γ fraction percentages was noticed after the placebo, but not the acute aronia juice treatment. According to the obtained results, long-term physical activity in recreational runners induces changes in serum protein profiles, probably due to the protein loss of low-weight proteins after exercise. At the same time, this study has shown that the acute consumption of aronia juice before intensive physical activity could exert a beneficial effect on post-exercise proteinuria.https://www.mdpi.com/2504-3900/91/1/196polyphenolsantioxidantssports nutrition
spellingShingle Marija Takić
Tamara Uzelac
Nevena Vidovic
Vuk Stevanovic
Ana Pantovic
Marija Glibetic
Vesna Jovanovic
Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles
Proceedings
polyphenols
antioxidants
sports nutrition
title Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles
title_full Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles
title_fullStr Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles
title_full_unstemmed Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles
title_short Acute Aronia Juice Consumption Prior to Half-Marathon Races Affects Proteinuria-Induced Changes of Serum Protein Profiles
title_sort acute aronia juice consumption prior to half marathon races affects proteinuria induced changes of serum protein profiles
topic polyphenols
antioxidants
sports nutrition
url https://www.mdpi.com/2504-3900/91/1/196
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