Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy

A 65-year-old woman who had been taking diclofenac for five years developed cramping central abdominal pain. Barium enema examination was negative, but colonoscopy revealed prominent mucosal folds in the right colon with areas of ulceration. Because of continued symptoms, a right hemicolectomy was p...

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Main Authors: Alan A Weiss, David A Owen
Format: Article
Language:English
Published: Wiley 1995-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1995/254254
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author Alan A Weiss
David A Owen
author_facet Alan A Weiss
David A Owen
author_sort Alan A Weiss
collection DOAJ
description A 65-year-old woman who had been taking diclofenac for five years developed cramping central abdominal pain. Barium enema examination was negative, but colonoscopy revealed prominent mucosal folds in the right colon with areas of ulceration. Because of continued symptoms, a right hemicolectomy was performed, which showed four separate short segment strictures or diaphragms. This case demonstrates a rare complication of nonsteroidal anti-inflammatory agent therapy that should be considered in the differential diagnosis of unexplained abdominal pain.
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spelling doaj-art-91dda7df80c04e5884634bc576d610982025-02-03T05:48:16ZengWileyCanadian Journal of Gastroenterology0835-79001995-01-019741341610.1155/1995/254254Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac TherapyAlan A Weiss0David A Owen1Departments of Medicine (Gastroenterology) and Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDepartments of Medicine (Gastroenterology) and Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaA 65-year-old woman who had been taking diclofenac for five years developed cramping central abdominal pain. Barium enema examination was negative, but colonoscopy revealed prominent mucosal folds in the right colon with areas of ulceration. Because of continued symptoms, a right hemicolectomy was performed, which showed four separate short segment strictures or diaphragms. This case demonstrates a rare complication of nonsteroidal anti-inflammatory agent therapy that should be considered in the differential diagnosis of unexplained abdominal pain.http://dx.doi.org/10.1155/1995/254254
spellingShingle Alan A Weiss
David A Owen
Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy
Canadian Journal of Gastroenterology
title Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy
title_full Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy
title_fullStr Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy
title_full_unstemmed Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy
title_short Colonic Diaphragm Disease in a Patient Receiving Long Term Diclofenac Therapy
title_sort colonic diaphragm disease in a patient receiving long term diclofenac therapy
url http://dx.doi.org/10.1155/1995/254254
work_keys_str_mv AT alanaweiss colonicdiaphragmdiseaseinapatientreceivinglongtermdiclofenactherapy
AT davidaowen colonicdiaphragmdiseaseinapatientreceivinglongtermdiclofenactherapy