KLF13 promotes ferroptosis and chemosensitivity in lung adenocarcinoma

KLF13 promotes ferroptosis and chemosensitivity in lung adenocarcinoma

Abstract Background Ferroptosis, a form of cell death reliant on iron metabolism dysregulation and lipid peroxidation, has emerged as a promising target for improving tumor drug resistance. This study aims to unveil the underlying molecular mechanisms of Kruppel-like factor 13 (KLF13) in ferroptosis...

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Bibliographic Details
Main Authors: Haochun Shi, Binyang Pan, Gujie Wu, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Shencheng Ren, Guoshu Bi, Cheng Zhan, Weigang Guo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
KLF13
Ferroptosis
Chemotherapy
GPX4
Lung adenocarcinoma
Online Access:https://doi.org/10.1186/s12915-025-02303-x
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