One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis
Abstract Background The aim of this study was to compare the surgical efficacy of one-stage and two-stage video-assisted thoracoscopic surgery (VATS) for bilateral multiple pulmonary nodules (BMPNs). Methods A retrospective analysis was made of 156 patients, 84 who underwent one-stage and 72 who und...
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| Language: | English |
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BMC
2025-01-01
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| Series: | World Journal of Surgical Oncology |
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| Online Access: | https://doi.org/10.1186/s12957-025-03660-1 |
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| author | Yu Han Fei Xiao Qianli Ma Zhenrong Zhang Zaiyong Wang Chaoyang Liang Deruo Liu |
| author_facet | Yu Han Fei Xiao Qianli Ma Zhenrong Zhang Zaiyong Wang Chaoyang Liang Deruo Liu |
| author_sort | Yu Han |
| collection | DOAJ |
| description | Abstract Background The aim of this study was to compare the surgical efficacy of one-stage and two-stage video-assisted thoracoscopic surgery (VATS) for bilateral multiple pulmonary nodules (BMPNs). Methods A retrospective analysis was made of 156 patients, 84 who underwent one-stage and 72 who underwent two-stage VATS for BMPNs at our department between January 2019 and December 2022. Perioperative and long-term outcomes were compared between the two groups using propensity score-matched (PSM) analysis. Results There were 48 patients in each group after PSM. No significant difference was observed in operation time, blood loss, rates of overall complications, and 3-year overall survival (p>0.05) between one-stage and two-stage groups. The one-stage procedure was associated with shorter length of stay (5 days [IQR 4-5.75 days] vs. 9 days [IQR 7–10 days]; p<0.001), as well as lower total cost (14626.3 ± 4149.4 vs. 18975.9 ± 3720.8 USD, p<0.001) compared to the two-stage procedure. The one-stage group was associated with better 3-year RFS compared with the two-stage group (90.7% vs. 75.3%, p = 0.039). Conclusion One-stage and two-stage VATS for BMPNs are both safe and feasible in selected patients. One-stage procedure possess potential advantages in reducing hospital stay and cost, as well as preventing tumor progression. |
| format | Article |
| id | doaj-art-91967ee6d2b4435e83da2421f7ec748f |
| institution | Kabale University |
| issn | 1477-7819 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | World Journal of Surgical Oncology |
| spelling | doaj-art-91967ee6d2b4435e83da2421f7ec748f2025-01-26T12:36:33ZengBMCWorld Journal of Surgical Oncology1477-78192025-01-012311710.1186/s12957-025-03660-1One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysisYu Han0Fei Xiao1Qianli Ma2Zhenrong Zhang3Zaiyong Wang4Chaoyang Liang5Deruo Liu6Department of General Thoracic Surgery, Friendship HospitalDepartment of General Thoracic Surgery, Friendship HospitalDepartment of General Thoracic Surgery, Friendship HospitalDepartment of General Thoracic Surgery, Friendship HospitalDepartment of General Thoracic Surgery, Friendship HospitalDepartment of General Thoracic Surgery, Friendship HospitalDepartment of General Thoracic Surgery, Friendship HospitalAbstract Background The aim of this study was to compare the surgical efficacy of one-stage and two-stage video-assisted thoracoscopic surgery (VATS) for bilateral multiple pulmonary nodules (BMPNs). Methods A retrospective analysis was made of 156 patients, 84 who underwent one-stage and 72 who underwent two-stage VATS for BMPNs at our department between January 2019 and December 2022. Perioperative and long-term outcomes were compared between the two groups using propensity score-matched (PSM) analysis. Results There were 48 patients in each group after PSM. No significant difference was observed in operation time, blood loss, rates of overall complications, and 3-year overall survival (p>0.05) between one-stage and two-stage groups. The one-stage procedure was associated with shorter length of stay (5 days [IQR 4-5.75 days] vs. 9 days [IQR 7–10 days]; p<0.001), as well as lower total cost (14626.3 ± 4149.4 vs. 18975.9 ± 3720.8 USD, p<0.001) compared to the two-stage procedure. The one-stage group was associated with better 3-year RFS compared with the two-stage group (90.7% vs. 75.3%, p = 0.039). Conclusion One-stage and two-stage VATS for BMPNs are both safe and feasible in selected patients. One-stage procedure possess potential advantages in reducing hospital stay and cost, as well as preventing tumor progression.https://doi.org/10.1186/s12957-025-03660-1Multiple primary lung cancersThoracoscopic surgeryBilateralOne-stageTwo-stage |
| spellingShingle | Yu Han Fei Xiao Qianli Ma Zhenrong Zhang Zaiyong Wang Chaoyang Liang Deruo Liu One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis World Journal of Surgical Oncology Multiple primary lung cancers Thoracoscopic surgery Bilateral One-stage Two-stage |
| title | One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis |
| title_full | One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis |
| title_fullStr | One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis |
| title_full_unstemmed | One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis |
| title_short | One-stage versus two-stage thoracoscopic surgery for synchronous bilateral pulmonary nodules: a propensity score-matched analysis |
| title_sort | one stage versus two stage thoracoscopic surgery for synchronous bilateral pulmonary nodules a propensity score matched analysis |
| topic | Multiple primary lung cancers Thoracoscopic surgery Bilateral One-stage Two-stage |
| url | https://doi.org/10.1186/s12957-025-03660-1 |
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