Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting
Objective: Inflammation plays an important role in the initiation of postoperative atrial fibrillation (PoAF) in individuals undergoing cardiac surgery, Thus, this study aimed to investigate the predictive value of the systemic immune inflammation index (SII) to develop PoAF in such patients. Metho...
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Galenos Publishing House
2021-12-01
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| Series: | Medeniyet Medical Journal |
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| author | Murat Selçuk Tufan Çınar Faysal Şaylık Selami Doğan Ismail Selçuk Ahmet L. Orhan |
| author_facet | Murat Selçuk Tufan Çınar Faysal Şaylık Selami Doğan Ismail Selçuk Ahmet L. Orhan |
| author_sort | Murat Selçuk |
| collection | DOAJ |
| description | Objective: Inflammation plays an important role in the initiation of postoperative atrial fibrillation (PoAF) in individuals undergoing cardiac surgery, Thus, this study aimed to investigate the predictive value of the systemic immune inflammation index (SII) to develop PoAF in such patients.
Methods: In total, 391 consecutive patients undergoing an isolated coronary artery bypass grafting (CABG) were retrospectively analyzed. PoAF was defined according to the current guideline. The SII is determined using the following equation: neutrophil (N) × platelet (P) ÷ lymphocyte (L).
Results: The incidence of PoAF in the present study was 24% (n=97 cases). Multivariate logistic regression analysis revealed that the SII was an independent predictor of PoAF (Odds ratio: 1.002 95% confidence interval: (1.001-1.002), p<0.01). The optimal value of the SII in detecting PoAF was established by a receiver operating characteristic curve assessment, and it was >807.8 with 60.8% sensitivity and 80.9% specificity [area under the curve (AUC): 0.7107]. The AUC value of SII in detecting PoAF was much greater than the AUC values of both the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) (AUC: 0.6740 and AUC: 0.6426, respectively).
Conclusions: This study revealed that SII was an independent predictor of PoAF in patients who were operated on for isolated CABG. Additionally, SII had a better discriminative ability for PoAF compared to either NLR or PLR among these cases. |
| format | Article |
| id | doaj-art-9185227a90dc43de8e3eeb558063e359 |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-9185227a90dc43de8e3eeb558063e3592025-02-02T16:16:39ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062021-12-0136431832410.4274/MMJ.galenos.2021.37998Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass GraftingMurat Selçuk0https://orcid.org/0000-0002-6386-0142Tufan Çınar1https://orcid.org/0000-0001-8188-5020Faysal Şaylık2https://orcid.org/0000-0003-3165-6769Selami Doğan3https://orcid.org/0000-0003-1170-4567Ismail Selçuk4https://orcid.org/0000-0001-6334-9881Ahmet L. Orhan5https://orcid.org/0000-0002-8617-3281University of Health Sciences Turkey, Istanbul Sultan 2. Abdulhamid Han Training and Research Hospital, Clinic of Cardiology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Sultan 2. Abdulhamid Han Training and Research Hospital, Clinic of Cardiology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Van Training and Research Hospital, Turkey, Clinic of Cardiology, Van, TurkeyUniversity of Health Sciences Turkey, Istanbul Sultan 2. Abdulhamid Han Training and Research Hospital, Clinic of Cardiology, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Sultan 2. Sultan Abdulhamid Training and Research Hospital, Clinic of Cardiovascular Surgery, Istanbul, TurkeyUniversity of Health Sciences Turkey, Istanbul Sultan 2. Abdulhamid Han Training and Research Hospital, Clinic of Cardiology, Istanbul, TurkeyObjective: Inflammation plays an important role in the initiation of postoperative atrial fibrillation (PoAF) in individuals undergoing cardiac surgery, Thus, this study aimed to investigate the predictive value of the systemic immune inflammation index (SII) to develop PoAF in such patients. Methods: In total, 391 consecutive patients undergoing an isolated coronary artery bypass grafting (CABG) were retrospectively analyzed. PoAF was defined according to the current guideline. The SII is determined using the following equation: neutrophil (N) × platelet (P) ÷ lymphocyte (L). Results: The incidence of PoAF in the present study was 24% (n=97 cases). Multivariate logistic regression analysis revealed that the SII was an independent predictor of PoAF (Odds ratio: 1.002 95% confidence interval: (1.001-1.002), p<0.01). The optimal value of the SII in detecting PoAF was established by a receiver operating characteristic curve assessment, and it was >807.8 with 60.8% sensitivity and 80.9% specificity [area under the curve (AUC): 0.7107]. The AUC value of SII in detecting PoAF was much greater than the AUC values of both the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) (AUC: 0.6740 and AUC: 0.6426, respectively). Conclusions: This study revealed that SII was an independent predictor of PoAF in patients who were operated on for isolated CABG. Additionally, SII had a better discriminative ability for PoAF compared to either NLR or PLR among these cases.https://medeniyetmedicaljournal.org/jvi.aspx?pdir=medeniyet&plng=eng&un=MEDJ-37998&look4=siipostoperative atrial fibrillationcoronary artery bypass graftingpredictive |
| spellingShingle | Murat Selçuk Tufan Çınar Faysal Şaylık Selami Doğan Ismail Selçuk Ahmet L. Orhan Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting Medeniyet Medical Journal sii postoperative atrial fibrillation coronary artery bypass grafting predictive |
| title | Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting |
| title_full | Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting |
| title_fullStr | Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting |
| title_full_unstemmed | Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting |
| title_short | Predictive Value of Systemic Immune Inflammation Index for Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting |
| title_sort | predictive value of systemic immune inflammation index for postoperative atrial fibrillation in patients undergoing isolated coronary artery bypass grafting |
| topic | sii postoperative atrial fibrillation coronary artery bypass grafting predictive |
| url | https://medeniyetmedicaljournal.org/jvi.aspx?pdir=medeniyet&plng=eng&un=MEDJ-37998&look4= |
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