Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies
ABSTRACT Background Chronic obstructive pulmonary disease (COPD) patients commonly exhibit significant morbidity and experience a diminished quality of life. Since there has been no prior research on pneumonia in our study population, we carried out this study to learn more about the situation. Meth...
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Wiley
2025-01-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.70395 |
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| author | Muhammad Muneeb Hassan Sheikh Muhammad Sikandar Farrukh Jamal Muhammad Ameeq Alpha Kargbo |
| author_facet | Muhammad Muneeb Hassan Sheikh Muhammad Sikandar Farrukh Jamal Muhammad Ameeq Alpha Kargbo |
| author_sort | Muhammad Muneeb Hassan |
| collection | DOAJ |
| description | ABSTRACT Background Chronic obstructive pulmonary disease (COPD) patients commonly exhibit significant morbidity and experience a diminished quality of life. Since there has been no prior research on pneumonia in our study population, we carried out this study to learn more about the situation. Methods A retrospective analysis of 912 COPD patients with CAP who were receiving ICS treatment at the DHQ Hospital in Muzaffargarh, Punjab, Pakistan was conducted. Study began in February 2022 and ended in February 2023. Using multinomial logistic regression, the odds ratio and relative risk and Kaplan–Meier curves showed time‐to‐death and recovery by COPD status. Results Patients with COPD having a smoking history from 25 pack years and above had 22.791 higher odds of CAP (95% CI: 20.413–31.515), 21.527 higher odds of HTN (95% CI: 12.323–57.103), 16.955 higher odds of diabetes (95% CI: 22.954–29.331), and 13.964 higher odds of death in severity without COVID‐19 vaccination (95% CI: 5.988–32.561) compared to patients with COPD having a smoking history from 10 to 15 pack years. Conclusion COPD patients with a shorter ICS duration had a lower CAP risk, and vice versa, while vaccinated patients had a less severe disease as compared to non‐vaccinated patients. |
| format | Article |
| id | doaj-art-9171223887014e7fb524d8b299199eb2 |
| institution | Kabale University |
| issn | 2398-8835 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
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| series | Health Science Reports |
| spelling | doaj-art-9171223887014e7fb524d8b299199eb22025-01-29T03:42:39ZengWileyHealth Science Reports2398-88352025-01-0181n/an/a10.1002/hsr2.70395Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention StrategiesMuhammad Muneeb Hassan0Sheikh Muhammad Sikandar1Farrukh Jamal2Muhammad Ameeq3Alpha Kargbo4Department of Statistics The Islamia University of Bahawalpur Bahawalpur PakistanDHQ Hospital Muzaffargarh Muzaffargarh Punjab PakistanDepartment of Statistics The Islamia University of Bahawalpur Bahawalpur PakistanDepartment of Statistics The Islamia University of Bahawalpur Bahawalpur PakistanDepartment of Physical and Natural Sciences Brikama Campus University of the Gambia Serrekunda GambiaABSTRACT Background Chronic obstructive pulmonary disease (COPD) patients commonly exhibit significant morbidity and experience a diminished quality of life. Since there has been no prior research on pneumonia in our study population, we carried out this study to learn more about the situation. Methods A retrospective analysis of 912 COPD patients with CAP who were receiving ICS treatment at the DHQ Hospital in Muzaffargarh, Punjab, Pakistan was conducted. Study began in February 2022 and ended in February 2023. Using multinomial logistic regression, the odds ratio and relative risk and Kaplan–Meier curves showed time‐to‐death and recovery by COPD status. Results Patients with COPD having a smoking history from 25 pack years and above had 22.791 higher odds of CAP (95% CI: 20.413–31.515), 21.527 higher odds of HTN (95% CI: 12.323–57.103), 16.955 higher odds of diabetes (95% CI: 22.954–29.331), and 13.964 higher odds of death in severity without COVID‐19 vaccination (95% CI: 5.988–32.561) compared to patients with COPD having a smoking history from 10 to 15 pack years. Conclusion COPD patients with a shorter ICS duration had a lower CAP risk, and vice versa, while vaccinated patients had a less severe disease as compared to non‐vaccinated patients.https://doi.org/10.1002/hsr2.70395community‐acquired pneumoniaCOPDcoronavirus disease 2019SARS‐CoV‐2smoking history |
| spellingShingle | Muhammad Muneeb Hassan Sheikh Muhammad Sikandar Farrukh Jamal Muhammad Ameeq Alpha Kargbo Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies Health Science Reports community‐acquired pneumonia COPD coronavirus disease 2019 SARS‐CoV‐2 smoking history |
| title | Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies |
| title_full | Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies |
| title_fullStr | Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies |
| title_full_unstemmed | Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies |
| title_short | Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Prevention Strategies |
| title_sort | chronic obstructive pulmonary disease patients with community acquired pneumonia on inhaled corticosteroid therapy a comprehensive analysis of risk factors disease burden and prevention strategies |
| topic | community‐acquired pneumonia COPD coronavirus disease 2019 SARS‐CoV‐2 smoking history |
| url | https://doi.org/10.1002/hsr2.70395 |
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