The effects of cycloprolylglycine and its analogues on brain monoaminergic systems in BALB/c mice

The effects of cycloprolylglycine and its analogues on brain monoaminergic systems in BALB/c mice

Effects of chronic cycloprolylglycine (CPG) and its analogues GZK-001 and GZK-002 treatment at the doses 1 and 2 mg/kg on levels of monoamines and their metabolites in BALB/c mice brain were determined by HPLC. Neurochemical data demonstrated that antidepressant-like effects of the peptides are medi...

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Bibliographic Details
Main Authors: A. A. Abdullina, E. V. Vasileva, V. S. Kudrin, V. B Narkevich, T. A. Gudasheva, K. N. Kolyasnikova, G. I. Kovalev
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2020-07-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
cycloprolylglycine
gzk-001
gzk-002
monoamines
frontal cortex
striatum
hippocampus
antidepressant-like activity
balb/c
Online Access:https://www.pharmacokinetica.ru/jour/article/view/233
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