Castleman's Disease: A Case Report of the Unicentric Type
Castleman's disease, or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been de...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2012/175272 |
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| author | J. Gomez-Ramirez M. Posada L. Sanchez-Urdazpal E. Martin-Perez L. Del Campo I. Garcia J. L. Martin E. Larrañaga |
| author_facet | J. Gomez-Ramirez M. Posada L. Sanchez-Urdazpal E. Martin-Perez L. Del Campo I. Garcia J. L. Martin E. Larrañaga |
| author_sort | J. Gomez-Ramirez |
| collection | DOAJ |
| description | Castleman's disease, or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been described: a unicentric presentation with the disease confined to a single anatomic lymph node and a multicentric presentation characterized by generalized lymphadenopathy and a more aggressive clinical course. Also, three histopathological subtypes have been described: hyaline-vascular, plasma cell, and a mixed variant. Preoperative diagnosis of hyaline-vascular Castleman's disease is difficult, and the definitive result is based on postoperative pathological findings. The gold standard therapy is the complete surgical excision. |
| format | Article |
| id | doaj-art-914d1de2bdd04a2d8b916f9dbfe74f5f |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-914d1de2bdd04a2d8b916f9dbfe74f5f2025-02-03T05:51:00ZengWileyCase Reports in Surgery2090-69002090-69192012-01-01201210.1155/2012/175272175272Castleman's Disease: A Case Report of the Unicentric TypeJ. Gomez-Ramirez0M. Posada1L. Sanchez-Urdazpal2E. Martin-Perez3L. Del Campo4I. Garcia5J. L. Martin6E. Larrañaga7Department of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of Radiology, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainDepartment of General Surgery, La Princesa University Hospital, 62 Diego de Leon Street, 28006 Madrid, SpainCastleman's disease, or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue related to the chronic human herpes virus 8 (HHV-8) infection and the human immunodeficiency virus (HIV). Two clinical entities have been described: a unicentric presentation with the disease confined to a single anatomic lymph node and a multicentric presentation characterized by generalized lymphadenopathy and a more aggressive clinical course. Also, three histopathological subtypes have been described: hyaline-vascular, plasma cell, and a mixed variant. Preoperative diagnosis of hyaline-vascular Castleman's disease is difficult, and the definitive result is based on postoperative pathological findings. The gold standard therapy is the complete surgical excision.http://dx.doi.org/10.1155/2012/175272 |
| spellingShingle | J. Gomez-Ramirez M. Posada L. Sanchez-Urdazpal E. Martin-Perez L. Del Campo I. Garcia J. L. Martin E. Larrañaga Castleman's Disease: A Case Report of the Unicentric Type Case Reports in Surgery |
| title | Castleman's Disease: A Case Report of the Unicentric Type |
| title_full | Castleman's Disease: A Case Report of the Unicentric Type |
| title_fullStr | Castleman's Disease: A Case Report of the Unicentric Type |
| title_full_unstemmed | Castleman's Disease: A Case Report of the Unicentric Type |
| title_short | Castleman's Disease: A Case Report of the Unicentric Type |
| title_sort | castleman s disease a case report of the unicentric type |
| url | http://dx.doi.org/10.1155/2012/175272 |
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