Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava
Paragangliomas are rare tumors originating outside of the adrenal medulla which can be associated with catecholamine secretion or mass effect, one of which typically leads to their discovery. The differences between these tumors and traditional intra-adrenal pheochromocytomas are a subject of recent...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2014/837054 |
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| author | E. M. Mannina Z. Xiong R. Self E. Kandil |
| author_facet | E. M. Mannina Z. Xiong R. Self E. Kandil |
| author_sort | E. M. Mannina |
| collection | DOAJ |
| description | Paragangliomas are rare tumors originating outside of the adrenal medulla which can be associated with catecholamine secretion or mass effect, one of which typically leads to their discovery. The differences between these tumors and traditional intra-adrenal pheochromocytomas are a subject of recent investigations. Standard of care therapy is medical management and surgical resection of the tumor. When tumors are biochemically active, medical optimization of the autonomic nervous system is a critical component to a safe, definitive resection. Tumors arising in the retroperitoneum present technical challenges for the surgeon as they are often large and difficult to access, making an oncologic resection much more difficult. Lastly, these tumors are mostly benign and rarely invade adjacent structures—an operative finding not always predicted by preoperative imaging—which, if present, adds significant complexity and risk to the resection. A case illustrating these challenges in the management of a biochemically active retroperitoneal paraganglioma invading the inferior vena cava follows. |
| format | Article |
| id | doaj-art-913852e3e8b946a9ad2189514873b593 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-913852e3e8b946a9ad2189514873b5932025-02-03T05:53:58ZengWileyCase Reports in Surgery2090-69002090-69192014-01-01201410.1155/2014/837054837054Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena CavaE. M. Mannina0Z. Xiong1R. Self2E. Kandil3Department of Radiation Oncology, Indiana University SOM, 535 Barnhill Drive, RT-041, Indianapolis, IN 46202, USADepartment of Pathology, Tulane University SOM, 1430 Tulane Avenue, SL-79, New Orleans, LA 70112, USADepartment of Pathology, Tulane University SOM, 1430 Tulane Avenue, SL-79, New Orleans, LA 70112, USADepartment of Surgery, Tulane University SOM, 1430 Tulane Avenue, SL-22, New Orleans, LA 70112, USAParagangliomas are rare tumors originating outside of the adrenal medulla which can be associated with catecholamine secretion or mass effect, one of which typically leads to their discovery. The differences between these tumors and traditional intra-adrenal pheochromocytomas are a subject of recent investigations. Standard of care therapy is medical management and surgical resection of the tumor. When tumors are biochemically active, medical optimization of the autonomic nervous system is a critical component to a safe, definitive resection. Tumors arising in the retroperitoneum present technical challenges for the surgeon as they are often large and difficult to access, making an oncologic resection much more difficult. Lastly, these tumors are mostly benign and rarely invade adjacent structures—an operative finding not always predicted by preoperative imaging—which, if present, adds significant complexity and risk to the resection. A case illustrating these challenges in the management of a biochemically active retroperitoneal paraganglioma invading the inferior vena cava follows.http://dx.doi.org/10.1155/2014/837054 |
| spellingShingle | E. M. Mannina Z. Xiong R. Self E. Kandil Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava Case Reports in Surgery |
| title | Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava |
| title_full | Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava |
| title_fullStr | Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava |
| title_full_unstemmed | Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava |
| title_short | Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena Cava |
| title_sort | resection of a catecholamine elaborating retroperitoneal paraganglioma invading the inferior vena cava |
| url | http://dx.doi.org/10.1155/2014/837054 |
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