Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing

Exploring changes in metabolites and fecal microbiota of advanced gastric cancer based on plasma metabolomics and 16S rDNA sequencing

Metabolomics and 16S rDNA sequencing have shown great potential in elucidating complex mechanisms associated with diseases. Currently, there is little research on the omics of gastric cancer and it lacks effective biomarkers. Objective: Based on plasma metabolomics and 16S rDNA sequencing to evaluat...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xinyi Feng, Yu Zhang, Jun Feng, Zhongjun Li, Zhi Zhang, Lin Zhu, Ruoyu Zhou, Haibo Wang, Xiaojun Dai, Yanqing Liu
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Series:	Heliyon
Subjects:	Plasma metabolomics 16S rDNA sequencing Gastric cancer Gut flora
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844025000957
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Exploring the Effects of <i>Gracilaria lemaneiformis</i> Polysaccharides on the Fecal Microbiota and Fecal Metabolites of Fattening Pigs Based on 16S rDNA and Metabolome Sequencing
by: Mingyang Jia, et al.
Published: (2025-01-01)

Exploring the effects of Tianma Gouteng granules on L-NAME-induced hypertensive rats based on 16S rDNA gene sequencing and metabolomics
by: Li Cheng, et al.
Published: (2025-01-01)

Combined metabolomics and 16S rDNA sequence analyses of the gut microbiome reveal the action mechanism of Fructus Akebiae against hepatic fibrosis
by: Rong-Rong Wu, et al.
Published: (2025-02-01)

Role of gut microbiota and fecal metabolites in the protective effect of soybean pulp-rich diet against estrogen-induced cholestasis in rats
by: Jiawei Wang, et al.
Published: (2025-01-01)

Species identification based on the fecal DNA samples of the Caprinae
by: Abdurakhim E. Kuchboev, et al.
Published: (2024-12-01)

Multi-Omics Insights into Rumen Microbiota and Metabolite Interactions Regulating Milk Fat Synthesis in Buffaloes
by: Ye Yu, et al.
Published: (2025-01-01)

Comparison of clinical metagenomics with 16S rDNA Sanger sequencing for the bacteriological diagnosis of culture-negative samples
by: Camille d’Humières, et al.
Published: (2025-03-01)

Effects of breaking up prolonged sitting via exercise snacks intervention on the body composition and plasma metabolomics of sedentary obese adults: a randomized controlled trial
by: Jianming Zhou, et al.
Published: (2025-02-01)

Human Milk Archaea Associated with Neonatal Gut Colonization and Its Co-Occurrence with Bacteria
by: Maricarmen Salas-López, et al.
Published: (2025-01-01)

Characteristics of tongue coating microbiota in diabetic and non-diabetic kidney patients receiving hemodialysis
by: Qiang Luo, et al.
Published: (2025-01-01)

Monitoring and identification of spoilage-related microorganisms in braised chicken with modified atmosphere packaging during refrigerated storage
by: Yang Lei, et al.
Published: (2023-01-01)

Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis
by: Xiaoxue Wang, et al.
Published: (2025-02-01)

High and Low Taxa Specificity of Rhizosphere Bacteria Communities of Mangrove (Rhizophora mucronata) from Kuala Langsa and Telaga Tujuh Island, East Aceh
by: Siti Maysaroh, et al.
Published: (2024-05-01)

Role of plasma metabolome in mediating the effect of plasma lipidome on NAFLD: a Mendelian randomization study
by: Zhuyuan Zheng, et al.
Published: (2025-01-01)

Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum
by: Han Zhao, et al.
Published: (2025-02-01)

Fecal microbiome change in patients with ulcerative colitis after fecal microbiota transplantation
by: A. Y. Tikunov, et al.
Published: (2020-04-01)

Gastric Microbiota Associated with Gastric Precancerous Lesions in <i>Helicobacter pylori</i>-Negative Patients
by: Han-Na Kim, et al.
Published: (2025-01-01)

Effects of rumen fluid transplantation on the fecal flora of yaks
by: Man Zhang, et al.
Published: (2025-01-01)

Widely targeted metabolomics analysis reveals the dynamically changes in volatile metabolites during xiaoqu baijiu fermentation
by: Zhenbing Ma, et al.
Published: (2025-01-01)

Gastric Microbiota in Patients with Dyspepsia: Metatranscriptomic Analysis
by: Е. А. Kupriyanova, et al.
Published: (2024-05-01)

Untargeted metabolomics and functional analyses reveal that the secondary metabolite quinic acid associates with Angelica sinensis flowering
by: Pei Liu, et al.
Published: (2025-01-01)

Comprehensive comparison on the chemical metabolites and taste evaluation of tea after roasting using untargeted and pseudotargeted metabolomics
by: Zongde Jiang, et al.
Published: (2022-05-01)

Modulatory effects of selenium nanoparticles on gut microbiota and metabolites of juvenile Nile tilapia (Oreochromis niloticus) by microbiome-metabolomic analysis
by: Jing Ni, et al.
Published: (2025-03-01)

Formulation, characterization, and evaluation of curcumin-loaded ginger-derived nanovesicles for anti-colitis activity
by: Shengjie Huang, et al.
Published: (2024-12-01)

Fecal metabolomics reveals the positive effect of ethanol extract of propolis on T2DM mice
by: Chunmei Wang, et al.
Published: (2023-01-01)

A new Leucoagaricus species of section Piloselli (Agaricales, Agaricaceae) from Spain
by: Marco Contu, et al.
Published: (2012-12-01)

Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection
by: Xinyi Shi, et al.
Published: (2025-01-01)

Comparative analysis of the intestinal flora of Siniperca chuatsi at different growth stages under three feeding practices
by: Yunyun Yan, et al.
Published: (2025-03-01)

Single‐Cell Simultaneous Metabolome and Transcriptome Profiling Revealing Metabolite‐Gene Correlation Network
by: Xiying Mao, et al.
Published: (2025-01-01)

Fecal Microbiome and Metabolomic Profiles of Mixed-Fed Infants Are More Similar to Formula-Fed than Breastfed Infants
by: Mei Wang, et al.
Published: (2025-01-01)

High-throughput untargeted metabolomics reveals metabolites and metabolic pathways that differentiate two divergent pig breeds
by: S. Bovo, et al.
Published: (2025-01-01)

Effects of dietary l-carnosine supplementation on the growth, intestinal microbiota, and serum metabolome of fattening lambs
by: Yaxuan Meng, et al.
Published: (2025-01-01)

Analysis of differential metabolites in Liuyang douchi at different fermentation stages based on untargeted metabolomics approach
by: Liwen Jiang, et al.
Published: (2025-01-01)

The characteristics of intestinal microflora in infants with rotavirus enteritis, changes in microflora before and after treatment and their clinical values
by: Qiyan Yan, et al.
Published: (2025-02-01)

Characterization and comparison of fecal microbiota in horses with pituitary pars intermedia dysfunction and age‐matched controls
by: Wenqing Wang, et al.
Published: (2025-01-01)

Assessment of Spoilage Microbiota of Rainbow Trout (Oncorhynchus mykiss) during Storage by 16S rDNA Sequencing
by: Guangqing Du, et al.
Published: (2022-01-01)

The gut–kidney axis is regulated by astragaloside IV to inhibit cyclosporine A-induced nephrotoxicity
by: Cong Han, et al.
Published: (2025-01-01)

Liquid Chromatography-Mass Spectrometry-Based Metabolomic Analysis of Metabolites and Metabolic Pathways of Selenium-Enriched Auricularia auricula
by: YUE Shibo, CUI Hang, SHEN Qin, CAO Dongmei,,,
Published: (2025-02-01)

Differences in Metabolites of Different Varieties from Xinjiang Large-fruit Sea Buckthorn as Analyzed by Non-targeted Metabolomics
by: Rong HAN, et al.
Published: (2025-02-01)

Exploratory profiling of metabolites in cerebrospinal fluid using a commercially available targeted LC-MS based metabolomics kit to discriminate leptomeningeal metastasis
by: Soojin Jang, et al.
Published: (2025-01-01)