PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response
Mitochondrial dysfunction is involved in numerous diseases and the aging process. The integrated stress response (ISR) serves as a critical adaptation mechanism to a variety of stresses, including those originating from mitochondria. By utilizing mass spectrometry-based cellular thermal shift assay...
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Main Authors: | Ling Cheng, Ian Meliala, Yidi Kong, Jingyuan Chen, Christopher G Proud, Mikael Björklund |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2025-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/102852 |
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