PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER
Pauciarticular juvenile arthritis associated with antinuclear factor and uveitis with onset at an early age has a special place in the structure of juvenile arthrites. This variant of arthritis is characterized by unpredictability of nosological outcomes and the prognosis is often associated with un...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2014-01-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/138 |
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| author | I. P. Nikishina S. V. Arsenyeva D. L. Alexeyev A. V. Smirnov |
| author_facet | I. P. Nikishina S. V. Arsenyeva D. L. Alexeyev A. V. Smirnov |
| author_sort | I. P. Nikishina |
| collection | DOAJ |
| description | Pauciarticular juvenile arthritis associated with antinuclear factor and uveitis with onset at an early age has a special place in the structure of juvenile arthrites. This variant of arthritis is characterized by unpredictability of nosological outcomes and the prognosis is often associated with unfavorable uveitis course. Joint syndrome is characterized by frequent dactylites, which are usually associated with psoriatic arthritis. The article presents clinical observation of a family case (mother and daughter) of juvenile arthritis with onset at an early age, eye lesion, homogenous clinical manifestations in the onset and manifestation of severe ankylosing spondylitis in the mother 25 years into the disease. Both patients started undergoing adalimumab therapy at the same time and very effectively. Clinical observation illustrates the need in timely prescription of a pathogenetically substantiated genetically engineered biological therapy in order to prevent incapacitation of patients with juvenile arthritis regarding condition of joints and organ of vision. |
| format | Article |
| id | doaj-art-912d4a5fdf274bb79a5f66d030e9a93b |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2014-01-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-912d4a5fdf274bb79a5f66d030e9a93b2025-08-20T03:36:53ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892014-01-01111445010.15690/pf.v11i1.894138PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHERI. P. Nikishina0S. V. Arsenyeva1D. L. Alexeyev2A. V. Smirnov3Nasonova Research Institute of Rheumatology, MoscowNasonova Research Institute of Rheumatology, Moscow, Russian FederationNasonova Research Institute of Rheumatology, Moscow, Russian FederationNasonova Research Institute of Rheumatology, Moscow, Russian FederationPauciarticular juvenile arthritis associated with antinuclear factor and uveitis with onset at an early age has a special place in the structure of juvenile arthrites. This variant of arthritis is characterized by unpredictability of nosological outcomes and the prognosis is often associated with unfavorable uveitis course. Joint syndrome is characterized by frequent dactylites, which are usually associated with psoriatic arthritis. The article presents clinical observation of a family case (mother and daughter) of juvenile arthritis with onset at an early age, eye lesion, homogenous clinical manifestations in the onset and manifestation of severe ankylosing spondylitis in the mother 25 years into the disease. Both patients started undergoing adalimumab therapy at the same time and very effectively. Clinical observation illustrates the need in timely prescription of a pathogenetically substantiated genetically engineered biological therapy in order to prevent incapacitation of patients with juvenile arthritis regarding condition of joints and organ of vision.https://www.pedpharma.ru/jour/article/view/138pauciarticular juvenile arthritispsoriatic arthritisuveitisgenetically engineered biological therapychildren |
| spellingShingle | I. P. Nikishina S. V. Arsenyeva D. L. Alexeyev A. V. Smirnov PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER Педиатрическая фармакология pauciarticular juvenile arthritis psoriatic arthritis uveitis genetically engineered biological therapy children |
| title | PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER |
| title_full | PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER |
| title_fullStr | PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER |
| title_full_unstemmed | PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER |
| title_short | PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER |
| title_sort | pauciarticular juvenile arthritis with anf associated uveitis clinical observation of a family case mother and daughter with ankylosing spondylitis in outcome in the mother |
| topic | pauciarticular juvenile arthritis psoriatic arthritis uveitis genetically engineered biological therapy children |
| url | https://www.pedpharma.ru/jour/article/view/138 |
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