False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report

Breast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Po...

Full description

Saved in:
Bibliographic Details
Main Authors: Gamze Uğurluer, Mustafa Kibar, Sinan Yavuz, Akin Kuzucu, Meltem Serin
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/459753
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832558813024092160
author Gamze Uğurluer
Mustafa Kibar
Sinan Yavuz
Akin Kuzucu
Meltem Serin
author_facet Gamze Uğurluer
Mustafa Kibar
Sinan Yavuz
Akin Kuzucu
Meltem Serin
author_sort Gamze Uğurluer
collection DOAJ
description Breast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Positron emission tomography with computed tomography detects malignancies using 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG PET CT) with high accuracy and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false positive metastatic mediastinal lymph nodes that were diagnosed by 18F-FDG PET CT in a 40-year-old breast cancer patient who had undergone preoperative evaluation. Right paratracheal, prevascular, aorticopulmonary, precarinal, subcarinal, hilar, and subhilar multiple conglomerated mediastinal lymph nodes were revealed in addition to left breast mass and axillary lymph nodes. Mediastinoscopy was performed with biopsy and pathology was reported as granulomatous lymphadenitis. In conclusion, any abnormal FDG accumulation in unusual lymph nodes must be evaluated carefully and confirmed histopathologically.
format Article
id doaj-art-9123fc92feeb498b9a5400c16a790c10
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-9123fc92feeb498b9a5400c16a790c102025-02-03T01:31:36ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/459753459753False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case ReportGamze Uğurluer0Mustafa Kibar1Sinan Yavuz2Akin Kuzucu3Meltem Serin4Department of Radiation Oncology, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, TurkeyDepartment of Nuclear Medicine, Acibadem Adana Hospital, Seyhan, 01130 Adana, TurkeyDepartment of Internal Medicine, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, TurkeyDepartment of Thoracic Surgery, Inonu University School of Medicine, 44000 Malatya, TurkeyDepartment of Radiation Oncology, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, TurkeyBreast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Positron emission tomography with computed tomography detects malignancies using 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG PET CT) with high accuracy and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false positive metastatic mediastinal lymph nodes that were diagnosed by 18F-FDG PET CT in a 40-year-old breast cancer patient who had undergone preoperative evaluation. Right paratracheal, prevascular, aorticopulmonary, precarinal, subcarinal, hilar, and subhilar multiple conglomerated mediastinal lymph nodes were revealed in addition to left breast mass and axillary lymph nodes. Mediastinoscopy was performed with biopsy and pathology was reported as granulomatous lymphadenitis. In conclusion, any abnormal FDG accumulation in unusual lymph nodes must be evaluated carefully and confirmed histopathologically.http://dx.doi.org/10.1155/2013/459753
spellingShingle Gamze Uğurluer
Mustafa Kibar
Sinan Yavuz
Akin Kuzucu
Meltem Serin
False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
Case Reports in Medicine
title False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
title_full False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
title_fullStr False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
title_full_unstemmed False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
title_short False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
title_sort false positive 18f fdg uptake in mediastinal lymph nodes detected with positron emission tomography in breast cancer a case report
url http://dx.doi.org/10.1155/2013/459753
work_keys_str_mv AT gamzeugurluer falsepositive18ffdguptakeinmediastinallymphnodesdetectedwithpositronemissiontomographyinbreastcanceracasereport
AT mustafakibar falsepositive18ffdguptakeinmediastinallymphnodesdetectedwithpositronemissiontomographyinbreastcanceracasereport
AT sinanyavuz falsepositive18ffdguptakeinmediastinallymphnodesdetectedwithpositronemissiontomographyinbreastcanceracasereport
AT akinkuzucu falsepositive18ffdguptakeinmediastinallymphnodesdetectedwithpositronemissiontomographyinbreastcanceracasereport
AT meltemserin falsepositive18ffdguptakeinmediastinallymphnodesdetectedwithpositronemissiontomographyinbreastcanceracasereport