False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report
Breast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Po...
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Wiley
2013-01-01
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Series: | Case Reports in Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/459753 |
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author | Gamze Uğurluer Mustafa Kibar Sinan Yavuz Akin Kuzucu Meltem Serin |
author_facet | Gamze Uğurluer Mustafa Kibar Sinan Yavuz Akin Kuzucu Meltem Serin |
author_sort | Gamze Uğurluer |
collection | DOAJ |
description | Breast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Positron emission tomography with computed tomography detects malignancies using 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG PET CT) with high accuracy and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false positive metastatic mediastinal lymph nodes that were diagnosed by 18F-FDG PET CT in a 40-year-old breast cancer patient who had undergone preoperative evaluation. Right paratracheal, prevascular, aorticopulmonary, precarinal, subcarinal, hilar, and subhilar multiple conglomerated mediastinal lymph nodes were revealed in addition to left breast mass and axillary lymph nodes. Mediastinoscopy was performed with biopsy and pathology was reported as granulomatous lymphadenitis. In conclusion, any abnormal FDG accumulation in unusual lymph nodes must be evaluated carefully and confirmed histopathologically. |
format | Article |
id | doaj-art-9123fc92feeb498b9a5400c16a790c10 |
institution | Kabale University |
issn | 1687-9627 1687-9635 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Medicine |
spelling | doaj-art-9123fc92feeb498b9a5400c16a790c102025-02-03T01:31:36ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/459753459753False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case ReportGamze Uğurluer0Mustafa Kibar1Sinan Yavuz2Akin Kuzucu3Meltem Serin4Department of Radiation Oncology, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, TurkeyDepartment of Nuclear Medicine, Acibadem Adana Hospital, Seyhan, 01130 Adana, TurkeyDepartment of Internal Medicine, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, TurkeyDepartment of Thoracic Surgery, Inonu University School of Medicine, 44000 Malatya, TurkeyDepartment of Radiation Oncology, Acibadem Adana Hospital, Acibadem University School of Medicine, Seyhan, 01130 Adana, TurkeyBreast cancer is the most frequently diagnosed cancer among females. It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. Accurate staging is important in determining prognosis and appropriate treatment. Positron emission tomography with computed tomography detects malignancies using 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG PET CT) with high accuracy and they contribute to decisions regarding diagnosis, staging, recurrence, and treatment response. Here, we report a case of false positive metastatic mediastinal lymph nodes that were diagnosed by 18F-FDG PET CT in a 40-year-old breast cancer patient who had undergone preoperative evaluation. Right paratracheal, prevascular, aorticopulmonary, precarinal, subcarinal, hilar, and subhilar multiple conglomerated mediastinal lymph nodes were revealed in addition to left breast mass and axillary lymph nodes. Mediastinoscopy was performed with biopsy and pathology was reported as granulomatous lymphadenitis. In conclusion, any abnormal FDG accumulation in unusual lymph nodes must be evaluated carefully and confirmed histopathologically.http://dx.doi.org/10.1155/2013/459753 |
spellingShingle | Gamze Uğurluer Mustafa Kibar Sinan Yavuz Akin Kuzucu Meltem Serin False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report Case Reports in Medicine |
title | False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report |
title_full | False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report |
title_fullStr | False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report |
title_full_unstemmed | False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report |
title_short | False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report |
title_sort | false positive 18f fdg uptake in mediastinal lymph nodes detected with positron emission tomography in breast cancer a case report |
url | http://dx.doi.org/10.1155/2013/459753 |
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