Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study
Abstract BackgroundAmblyopia is a common cause of visual impairment in children. Compliance with traditional treatments for amblyopia is challenging due to negative psychosocial impacts. Recent shifts in amblyopia treatment have moved from suppressing the dominant eye to enhan...
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| Format: | Article |
| Language: | English |
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JMIR Publications
2025-01-01
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| Series: | JMIR Serious Games |
| Online Access: | https://games.jmir.org/2025/1/e63384 |
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| _version_ | 1832585140538179584 |
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| author | Wenqing Zhu Shuneng Gu Jian Li Jin Lin Chanling Hu Rui Liu |
| author_facet | Wenqing Zhu Shuneng Gu Jian Li Jin Lin Chanling Hu Rui Liu |
| author_sort | Wenqing Zhu |
| collection | DOAJ |
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Abstract
BackgroundAmblyopia is a common cause of visual impairment in children. Compliance with traditional treatments for amblyopia is challenging due to negative psychosocial impacts. Recent shifts in amblyopia treatment have moved from suppressing the dominant eye to enhancing binocular visual function. Binocular digital therapy has become a promising approach.
ObjectiveThe aim of this study was to evaluate the effects of binocular gamified digital therapy on visual acuity and stereoacuity (SA) in children with unilateral amblyopia.
MethodsThis pilot prospective study enrolled 11 children aged 4-6 years with unilateral amblyopia. Following at least 8 weeks of refractive correction, participants underwent binocular gamified digital therapy for 60 minutes per day, 5 days a week. The therapy used a roguelike shooting game delivered under binocular conditions through two independent channels with a real-time artificial intelligence visual engine. Assessments of distance visual acuity (DVA), near visual acuity (NVA), and SA were conducted at baseline and again at 4, 8, and 12 weeks.
ResultsAt 12 weeks, the following significant improvements were noted: amblyopic eye DVA improved by 1.0 line (PdPdPdPdPd
ConclusionsBinocular gamified digital therapy is effective and safe for improving visual outcomes in children aged 4-6 years with unilateral amblyopia. |
| format | Article |
| id | doaj-art-9119ea49078e42718241c6111bfd729c |
| institution | Kabale University |
| issn | 2291-9279 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | JMIR Publications |
| record_format | Article |
| series | JMIR Serious Games |
| spelling | doaj-art-9119ea49078e42718241c6111bfd729c2025-01-27T02:47:47ZengJMIR PublicationsJMIR Serious Games2291-92792025-01-0113e63384e6338410.2196/63384Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety StudyWenqing Zhuhttp://orcid.org/0000-0003-4292-9507Shuneng Guhttp://orcid.org/0000-0003-4734-6351Jian Lihttp://orcid.org/0009-0003-2421-5890Jin Linhttp://orcid.org/0009-0001-0114-778XChanling Huhttp://orcid.org/0009-0000-3435-6935Rui Liuhttp://orcid.org/0000-0002-4092-2339 Abstract BackgroundAmblyopia is a common cause of visual impairment in children. Compliance with traditional treatments for amblyopia is challenging due to negative psychosocial impacts. Recent shifts in amblyopia treatment have moved from suppressing the dominant eye to enhancing binocular visual function. Binocular digital therapy has become a promising approach. ObjectiveThe aim of this study was to evaluate the effects of binocular gamified digital therapy on visual acuity and stereoacuity (SA) in children with unilateral amblyopia. MethodsThis pilot prospective study enrolled 11 children aged 4-6 years with unilateral amblyopia. Following at least 8 weeks of refractive correction, participants underwent binocular gamified digital therapy for 60 minutes per day, 5 days a week. The therapy used a roguelike shooting game delivered under binocular conditions through two independent channels with a real-time artificial intelligence visual engine. Assessments of distance visual acuity (DVA), near visual acuity (NVA), and SA were conducted at baseline and again at 4, 8, and 12 weeks. ResultsAt 12 weeks, the following significant improvements were noted: amblyopic eye DVA improved by 1.0 line (PdPdPdPdPd ConclusionsBinocular gamified digital therapy is effective and safe for improving visual outcomes in children aged 4-6 years with unilateral amblyopia.https://games.jmir.org/2025/1/e63384 |
| spellingShingle | Wenqing Zhu Shuneng Gu Jian Li Jin Lin Chanling Hu Rui Liu Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study JMIR Serious Games |
| title | Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study |
| title_full | Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study |
| title_fullStr | Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study |
| title_full_unstemmed | Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study |
| title_short | Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study |
| title_sort | transformative gamified binocular therapy for unilateral amblyopia in young children pilot prospective efficacy and safety study |
| url | https://games.jmir.org/2025/1/e63384 |
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