What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research

With the rising global prevalence of antibiotic resistance, the eradication rate of Helicobacter pylori (HP) is continuing to decrease. Probiotics are beneficial to human health and may be an adjunct therapy to increase the eradication rate of HP, lower treatment-associated side effects, and reduce...

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Main Authors: Han-Yi Song, Long Zhou, Dong-yan Liu, Xin-Jie Yao, Yan Li
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/9379480
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author Han-Yi Song
Long Zhou
Dong-yan Liu
Xin-Jie Yao
Yan Li
author_facet Han-Yi Song
Long Zhou
Dong-yan Liu
Xin-Jie Yao
Yan Li
author_sort Han-Yi Song
collection DOAJ
description With the rising global prevalence of antibiotic resistance, the eradication rate of Helicobacter pylori (HP) is continuing to decrease. Probiotics are beneficial to human health and may be an adjunct therapy to increase the eradication rate of HP, lower treatment-associated side effects, and reduce HP-associated gastric inflammation. However, inconsistent test results have prevented conclusions about the therapeutic prowess of probiotics for HP. The mechanisms of actions of probiotics include the production of substances that inhibit or kill HP or compete with HP for the adhesion site on gastric epithelial cells. Probiotics can also reduce the release of inflammatory factors by regulating the local immune response of the host. We searched the available literature for full-length articles focusing on the role of probiotics in HP management. This review presents the latest advances in this area.
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institution Kabale University
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publishDate 2018-01-01
publisher Wiley
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series Gastroenterology Research and Practice
spelling doaj-art-91163965f544460593d09c7fc36d921e2025-02-03T06:01:41ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/93794809379480What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing ResearchHan-Yi Song0Long Zhou1Dong-yan Liu2Xin-Jie Yao3Yan Li4Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, ChinaMedical Research Center, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, ChinaWith the rising global prevalence of antibiotic resistance, the eradication rate of Helicobacter pylori (HP) is continuing to decrease. Probiotics are beneficial to human health and may be an adjunct therapy to increase the eradication rate of HP, lower treatment-associated side effects, and reduce HP-associated gastric inflammation. However, inconsistent test results have prevented conclusions about the therapeutic prowess of probiotics for HP. The mechanisms of actions of probiotics include the production of substances that inhibit or kill HP or compete with HP for the adhesion site on gastric epithelial cells. Probiotics can also reduce the release of inflammatory factors by regulating the local immune response of the host. We searched the available literature for full-length articles focusing on the role of probiotics in HP management. This review presents the latest advances in this area.http://dx.doi.org/10.1155/2018/9379480
spellingShingle Han-Yi Song
Long Zhou
Dong-yan Liu
Xin-Jie Yao
Yan Li
What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
Gastroenterology Research and Practice
title What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
title_full What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
title_fullStr What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
title_full_unstemmed What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
title_short What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research
title_sort what roles do probiotics play in the eradication of helicobacter pylori current knowledge and ongoing research
url http://dx.doi.org/10.1155/2018/9379480
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