An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting

Over the past few years, malingered psychosis has had a progressive occurrence since a great deal of attention has been directed to the closures of long-stay psychiatric institutions and care in the community. Therefore, malingered psychosis needs to be identified to conduct precise forensic assessm...

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Main Authors: Mohsen Khosravi, Domenico De Berardis, Sahel Sarabandi, Sakineh Mazloom, Amir Adibi, Negin Javan, Zahra Ghiasi, Mohammad Nafeli, Negar Rahmanian
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Mental Illness
Online Access:http://dx.doi.org/10.1155/2024/5595195
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author Mohsen Khosravi
Domenico De Berardis
Sahel Sarabandi
Sakineh Mazloom
Amir Adibi
Negin Javan
Zahra Ghiasi
Mohammad Nafeli
Negar Rahmanian
author_facet Mohsen Khosravi
Domenico De Berardis
Sahel Sarabandi
Sakineh Mazloom
Amir Adibi
Negin Javan
Zahra Ghiasi
Mohammad Nafeli
Negar Rahmanian
author_sort Mohsen Khosravi
collection DOAJ
description Over the past few years, malingered psychosis has had a progressive occurrence since a great deal of attention has been directed to the closures of long-stay psychiatric institutions and care in the community. Therefore, malingered psychosis needs to be identified to conduct precise forensic assessments and prevent miscarriages of justice and misuse of restricted healthcare resources. Although, over the past decades, researchers have introduced a number of workable psychometric strategies and tools for diagnosing true psychosis, it is still sometimes challenging to differentiate between true and malingered psychosis. Hence, identifying reliable and innovative diagnostic alternatives seems crucial. Accordingly, a summary of gathered evidence is provided by the present review for enhancing future evaluation of oropharyngeal microbiome composition as a practical indicator for diagnosing true psychosis in a forensic psychiatric setting. As per the systematic search terms (namely, “diagnostic marker,” “oropharyngeal microbiome,” “forensic psychiatric setting,” “psychosis,” and “oropharyngeal microbiota”), relevant English publications were searched from January 1, 1980, to September 15, 2023, in Scopus, the Web of Science, Embase, Cochrane Library, PubMed, and Google Scholar databases. Finally, eight articles were included in the present review. Also, we adopted the narrative technique so that the material synthesis leads to a cohesive and compelling story. The results revealed that the periodontal disease and saliva microbiome were possibly associated with true psychosis. Thus, since oropharyngeal microbial compositions are highly different among healthy controls and patients with true psychosis, future research can take advantage of saliva to differentiate between fake and true fake psychosis throughout the initial stages of forensic psychiatric assessment. As a substrate of interest, saliva could also be used for characterizing the various stages of psychosis under a forensic psychiatric setting.
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spelling doaj-art-9114d8d4985745f4828be28c24ccd1362025-02-03T01:32:20ZengWileyMental Illness2036-74652024-01-01202410.1155/2024/5595195An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric SettingMohsen Khosravi0Domenico De Berardis1Sahel Sarabandi2Sakineh Mazloom3Amir Adibi4Negin Javan5Zahra Ghiasi6Mohammad Nafeli7Negar Rahmanian8Department of PsychiatryDepartment of PsychiatryDepertment of Clinical BiochemistryDepartment of NursingDepartment of PsychiatryDepartment of PsychologyDepartment of PsychiatryDepartment of PsychiatryDepartment of PsychiatryOver the past few years, malingered psychosis has had a progressive occurrence since a great deal of attention has been directed to the closures of long-stay psychiatric institutions and care in the community. Therefore, malingered psychosis needs to be identified to conduct precise forensic assessments and prevent miscarriages of justice and misuse of restricted healthcare resources. Although, over the past decades, researchers have introduced a number of workable psychometric strategies and tools for diagnosing true psychosis, it is still sometimes challenging to differentiate between true and malingered psychosis. Hence, identifying reliable and innovative diagnostic alternatives seems crucial. Accordingly, a summary of gathered evidence is provided by the present review for enhancing future evaluation of oropharyngeal microbiome composition as a practical indicator for diagnosing true psychosis in a forensic psychiatric setting. As per the systematic search terms (namely, “diagnostic marker,” “oropharyngeal microbiome,” “forensic psychiatric setting,” “psychosis,” and “oropharyngeal microbiota”), relevant English publications were searched from January 1, 1980, to September 15, 2023, in Scopus, the Web of Science, Embase, Cochrane Library, PubMed, and Google Scholar databases. Finally, eight articles were included in the present review. Also, we adopted the narrative technique so that the material synthesis leads to a cohesive and compelling story. The results revealed that the periodontal disease and saliva microbiome were possibly associated with true psychosis. Thus, since oropharyngeal microbial compositions are highly different among healthy controls and patients with true psychosis, future research can take advantage of saliva to differentiate between fake and true fake psychosis throughout the initial stages of forensic psychiatric assessment. As a substrate of interest, saliva could also be used for characterizing the various stages of psychosis under a forensic psychiatric setting.http://dx.doi.org/10.1155/2024/5595195
spellingShingle Mohsen Khosravi
Domenico De Berardis
Sahel Sarabandi
Sakineh Mazloom
Amir Adibi
Negin Javan
Zahra Ghiasi
Mohammad Nafeli
Negar Rahmanian
An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting
Mental Illness
title An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting
title_full An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting
title_fullStr An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting
title_full_unstemmed An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting
title_short An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Setting
title_sort update review to cast light on the possible role of altered oropharyngeal microbiota in differentiating true psychosis from malingered psychosis in a forensic psychiatric setting
url http://dx.doi.org/10.1155/2024/5595195
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