Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review

Congenital malaria is the presence of malaria parasites in a blood smear obtained from a neonate usually within 24 hours to 7 days of life. It has for long been regarded a rare condition. However, recent data indicate that congenital malaria complicates around 35.9% of live births globally, 0–37% in...

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Main Authors: Dickson Kajoba, Walufu Ivan Egesa, Habonimana Jean Petit, Muhiadin Omar Matan, Goretty Laker, William Mugowa Waibi, Daniel Asiimwe
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/9960006
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author Dickson Kajoba
Walufu Ivan Egesa
Habonimana Jean Petit
Muhiadin Omar Matan
Goretty Laker
William Mugowa Waibi
Daniel Asiimwe
author_facet Dickson Kajoba
Walufu Ivan Egesa
Habonimana Jean Petit
Muhiadin Omar Matan
Goretty Laker
William Mugowa Waibi
Daniel Asiimwe
author_sort Dickson Kajoba
collection DOAJ
description Congenital malaria is the presence of malaria parasites in a blood smear obtained from a neonate usually within 24 hours to 7 days of life. It has for long been regarded a rare condition. However, recent data indicate that congenital malaria complicates around 35.9% of live births globally, 0–37% in Sub-Saharan Africa and about 4–6.1% in Eastern Uganda. We present a 2-day-old neonate who presented with fever, irritability, and failure to breastfeed. Laboratory tests indicated that the neonate had a positive Giemsa-stained peripheral smear for Plasmodium falciparum, with a positive malaria rapid diagnostic test (MRDT) for P. falciparum malaria. The mother had a negative peripheral film for malaria and a negative MRDT. The neonate was managed with intravenous artesunate with improvement.
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publishDate 2021-01-01
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series Case Reports in Infectious Diseases
spelling doaj-art-90fe8afce48c44299c0f7aa40459f11e2025-02-03T07:23:59ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/99600069960006Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature ReviewDickson Kajoba0Walufu Ivan Egesa1Habonimana Jean Petit2Muhiadin Omar Matan3Goretty Laker4William Mugowa Waibi5Daniel Asiimwe6Department of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaDepartment of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaDepartment of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaDepartment of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaDepartment of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaDepartment of Paediatrics and Child Health, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaDepartment of Surgery, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, UgandaCongenital malaria is the presence of malaria parasites in a blood smear obtained from a neonate usually within 24 hours to 7 days of life. It has for long been regarded a rare condition. However, recent data indicate that congenital malaria complicates around 35.9% of live births globally, 0–37% in Sub-Saharan Africa and about 4–6.1% in Eastern Uganda. We present a 2-day-old neonate who presented with fever, irritability, and failure to breastfeed. Laboratory tests indicated that the neonate had a positive Giemsa-stained peripheral smear for Plasmodium falciparum, with a positive malaria rapid diagnostic test (MRDT) for P. falciparum malaria. The mother had a negative peripheral film for malaria and a negative MRDT. The neonate was managed with intravenous artesunate with improvement.http://dx.doi.org/10.1155/2021/9960006
spellingShingle Dickson Kajoba
Walufu Ivan Egesa
Habonimana Jean Petit
Muhiadin Omar Matan
Goretty Laker
William Mugowa Waibi
Daniel Asiimwe
Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review
Case Reports in Infectious Diseases
title Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review
title_full Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review
title_fullStr Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review
title_full_unstemmed Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review
title_short Congenital Malaria in a 2-Day-Old Neonate: A Case Report and Literature Review
title_sort congenital malaria in a 2 day old neonate a case report and literature review
url http://dx.doi.org/10.1155/2021/9960006
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