A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion
Carcinosarcoma is a rare biphasic neoplasia containing both malignant mesenchymal and epithelial elements. Bladder carcinosarcoma commonly presented as high-grade, advanced stage, and aggressive behavior with a poor prognosis. An 83-year-old male presented with painless gross hematuria to our hospit...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/349518 |
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| _version_ | 1832559087542337536 |
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| author | Masayoshi Zaitsu Mariko Yamanoi Koji Mikami Akiko Tonooka Toshimasa Uekusa Takumi Takeuchi |
| author_facet | Masayoshi Zaitsu Mariko Yamanoi Koji Mikami Akiko Tonooka Toshimasa Uekusa Takumi Takeuchi |
| author_sort | Masayoshi Zaitsu |
| collection | DOAJ |
| description | Carcinosarcoma is a rare biphasic neoplasia containing both malignant mesenchymal and epithelial elements. Bladder carcinosarcoma commonly presented as high-grade, advanced stage, and aggressive behavior with a poor prognosis. An 83-year-old male presented with painless gross hematuria to our hospital. Cystoscopy revealed massive nonpapillary bladder tumor on the right wall. The 91 g tumor could be completely removed with transurethral resection. Histology of the tumor was diagnosed as carcinosarcoma with no submucosal invasion composed of biphasic malignant epithelial and mesenchymal cells. Epithelial malignancy was urothelial cancer and mesenchymal one was chondrosarcoma and leiomyosarcoma. The specimens taken at the second-look TUR-Bt revealed that carcinoma in situ (urothelial cancer) but not sarcoma existed at the mucosa surrounding the previous tumor site. 80 mg of BCG instillation intravesically every week for six weeks was successfully administered to the patient. There is no tumor recurrence for 6 months after treatments. |
| format | Article |
| id | doaj-art-90e4c8b307324bdf947014746451c034 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-90e4c8b307324bdf947014746451c0342025-02-03T01:30:53ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/349518349518A Case of Giant Bladder Carcinosarcoma without Submucosal InvasionMasayoshi Zaitsu0Mariko Yamanoi1Koji Mikami2Akiko Tonooka3Toshimasa Uekusa4Takumi Takeuchi5Department of Urology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, JapanDepartment of Urology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, JapanDepartment of Urology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, JapanDepartment of Pathology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, JapanDepartment of Pathology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, JapanDepartment of Urology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-Cho, Nakahara-ku, Kawasaki 211-8510, JapanCarcinosarcoma is a rare biphasic neoplasia containing both malignant mesenchymal and epithelial elements. Bladder carcinosarcoma commonly presented as high-grade, advanced stage, and aggressive behavior with a poor prognosis. An 83-year-old male presented with painless gross hematuria to our hospital. Cystoscopy revealed massive nonpapillary bladder tumor on the right wall. The 91 g tumor could be completely removed with transurethral resection. Histology of the tumor was diagnosed as carcinosarcoma with no submucosal invasion composed of biphasic malignant epithelial and mesenchymal cells. Epithelial malignancy was urothelial cancer and mesenchymal one was chondrosarcoma and leiomyosarcoma. The specimens taken at the second-look TUR-Bt revealed that carcinoma in situ (urothelial cancer) but not sarcoma existed at the mucosa surrounding the previous tumor site. 80 mg of BCG instillation intravesically every week for six weeks was successfully administered to the patient. There is no tumor recurrence for 6 months after treatments.http://dx.doi.org/10.1155/2011/349518 |
| spellingShingle | Masayoshi Zaitsu Mariko Yamanoi Koji Mikami Akiko Tonooka Toshimasa Uekusa Takumi Takeuchi A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion Case Reports in Medicine |
| title | A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion |
| title_full | A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion |
| title_fullStr | A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion |
| title_full_unstemmed | A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion |
| title_short | A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion |
| title_sort | case of giant bladder carcinosarcoma without submucosal invasion |
| url | http://dx.doi.org/10.1155/2011/349518 |
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