Stage-dependent changes in culture medium osmolality promote porcine oocyte maturation in vitro

Stage-dependent changes in culture medium osmolality promote porcine oocyte maturation in vitro

IntroductionEarly preimplantation embryos of mammals exhibit pronounced sensitivity to hyperosmotic conditions, which results in an embryonic developmental block. The reduction of medium osmolarity or the supplementation with organic osmolytes can eliminate this arrest. Therefore, cell volume homeos...

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Bibliographic Details
Main Authors: Lixiang Liu, Yu Tang, Jing Shao, Bingfeng Fan, Yifeng Yang, Ying Zhang, Xiangyuan Zhao, Hailong Xue, Huimin Sun, Xulin Zhang, Yushi Zhang, Baozeng Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
porcine oocytes
cell volume regulation
osmolarity
glycine
in vitro maturation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1524749/full
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