Catalase Biomimetic Sensor Based on Metal
The development of motivated biosensors associated with the study of a large number of different substances is one of the most important areas of development of analytical chemistry. This goal in the development of certain biosensors was necessary for a sufficiently clear, fast, qualitative and quan...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | BIO Web of Conferences |
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| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04016.pdf |
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| author | Malikova Nurana Nahmad Gurbanova Lala Maharram Ali-Zadeh Nahmad Islam Nagiev Tofik Murtuza Shokhzod Ulashov Kurbanova Shaxnoza |
| author_facet | Malikova Nurana Nahmad Gurbanova Lala Maharram Ali-Zadeh Nahmad Islam Nagiev Tofik Murtuza Shokhzod Ulashov Kurbanova Shaxnoza |
| author_sort | Malikova Nurana Nahmad |
| collection | DOAJ |
| description | The development of motivated biosensors associated with the study of a large number of different substances is one of the most important areas of development of analytical chemistry. This goal in the development of certain biosensors was necessary for a sufficiently clear, fast, qualitative and quantitative determination of the desired component. Chemical reactions in living organisms are carried out with the help of catalysts - enzymes. Enzymes are proteins with prosthetic groups, and proteins are polymers formed from amino acid links. The number of different enzymes in a cell is the same as the number of different chemical reactions that occur in it. This work is devoted to the study of biomimetic sensors, where metals (Pb, Ag, Al) were used as a converter. The active material was iron tetraphenylporphyrin adsorbed on Al2O3. It was found that biomimetic sensors made on the basis of intelligent material (TPhPFe3+/Al2O3) and metals have a number of technological advantages. The developed biomimetic sensors are characterized by high sensitivity, activity, stability and reproducibility. When detecting the catalase activity of biomimetic sensors, the maximum sensitivity to the concentration of H2O2 in an aqueous solution for TPhPFe3+/Al2O3//Pb was 10-8wt.%, for TPhPFe3+/Al2O3//Ag – 10-8wt.%, for TPhPFe3+/Al2O3//Al – 10-6 wt.%. |
| format | Article |
| id | doaj-art-90cff320d61a41a3b167b78d05902442 |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-90cff320d61a41a3b167b78d059024422025-02-05T10:42:42ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011510401610.1051/bioconf/202515104016bioconf_mblc2024_04016Catalase Biomimetic Sensor Based on MetalMalikova Nurana Nahmad0Gurbanova Lala Maharram1Ali-Zadeh Nahmad Islam2Nagiev Tofik Murtuza3Shokhzod Ulashov4Kurbanova Shaxnoza5Nagiev Institute of Catalysis and Inorganic Chemistry of Ministry of Science and EducationWestern Caspian UniversityNagiev Institute of Catalysis and Inorganic Chemistry of Ministry of Science and EducationNagiev Institute of Catalysis and Inorganic Chemistry of Ministry of Science and EducationSamarkand State Medical UniversityOriental UniversityThe development of motivated biosensors associated with the study of a large number of different substances is one of the most important areas of development of analytical chemistry. This goal in the development of certain biosensors was necessary for a sufficiently clear, fast, qualitative and quantitative determination of the desired component. Chemical reactions in living organisms are carried out with the help of catalysts - enzymes. Enzymes are proteins with prosthetic groups, and proteins are polymers formed from amino acid links. The number of different enzymes in a cell is the same as the number of different chemical reactions that occur in it. This work is devoted to the study of biomimetic sensors, where metals (Pb, Ag, Al) were used as a converter. The active material was iron tetraphenylporphyrin adsorbed on Al2O3. It was found that biomimetic sensors made on the basis of intelligent material (TPhPFe3+/Al2O3) and metals have a number of technological advantages. The developed biomimetic sensors are characterized by high sensitivity, activity, stability and reproducibility. When detecting the catalase activity of biomimetic sensors, the maximum sensitivity to the concentration of H2O2 in an aqueous solution for TPhPFe3+/Al2O3//Pb was 10-8wt.%, for TPhPFe3+/Al2O3//Ag – 10-8wt.%, for TPhPFe3+/Al2O3//Al – 10-6 wt.%.https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04016.pdfbiomimeticsensortetraphenylporphyrin of ironcatalasesmart material |
| spellingShingle | Malikova Nurana Nahmad Gurbanova Lala Maharram Ali-Zadeh Nahmad Islam Nagiev Tofik Murtuza Shokhzod Ulashov Kurbanova Shaxnoza Catalase Biomimetic Sensor Based on Metal BIO Web of Conferences biomimetic sensor tetraphenylporphyrin of iron catalase smart material |
| title | Catalase Biomimetic Sensor Based on Metal |
| title_full | Catalase Biomimetic Sensor Based on Metal |
| title_fullStr | Catalase Biomimetic Sensor Based on Metal |
| title_full_unstemmed | Catalase Biomimetic Sensor Based on Metal |
| title_short | Catalase Biomimetic Sensor Based on Metal |
| title_sort | catalase biomimetic sensor based on metal |
| topic | biomimetic sensor tetraphenylporphyrin of iron catalase smart material |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04016.pdf |
| work_keys_str_mv | AT malikovanurananahmad catalasebiomimeticsensorbasedonmetal AT gurbanovalalamaharram catalasebiomimeticsensorbasedonmetal AT alizadehnahmadislam catalasebiomimeticsensorbasedonmetal AT nagievtofikmurtuza catalasebiomimeticsensorbasedonmetal AT shokhzodulashov catalasebiomimeticsensorbasedonmetal AT kurbanovashaxnoza catalasebiomimeticsensorbasedonmetal |