Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems

Milk is considered an important source of protein in human diets. As the major protein component in milk, casein has attracted extensive attention from scholars due to its biparental structure and self-assembly properties. However, the poor pH, Ca2+, and temperature stability of casein micelles limi...

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Main Author: YE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo
Format: Article
Language:English
Published: China Food Publishing Company 2025-06-01
Series:Shipin Kexue
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Online Access:https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-12-042.pdf
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author YE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo
author_facet YE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo
author_sort YE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo
collection DOAJ
description Milk is considered an important source of protein in human diets. As the major protein component in milk, casein has attracted extensive attention from scholars due to its biparental structure and self-assembly properties. However, the poor pH, Ca2+, and temperature stability of casein micelles limit their application in delivery systems. This article systematically introduces the structural types of casein, the methods for its structural analysis, the methods for its modification based on the defects of micelle properties and their subsequent applications, aiming to prove the huge potential of casein micelles as delivery systems for bioactive compounds. Furthermore, this review provides an outlook on the future development of casein micelle systems in the field of functional food ingredients.
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institution DOAJ
issn 1002-6630
language English
publishDate 2025-06-01
publisher China Food Publishing Company
record_format Article
series Shipin Kexue
spelling doaj-art-90b8aeee40ff43daa4f4a1b930fbca352025-08-20T03:12:32ZengChina Food Publishing CompanyShipin Kexue1002-66302025-06-01461237939010.7506/spkx1002-6630-20241214-124Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery SystemsYE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo0(Key Laboratory of Fruit and Vegetable Processing, Ministry of Agriculture and Rural Affairs, National Engineering Research Center for Fruit and Vegetable Processing, College of Food Science and Nutrition Engineering, China Agricultural University, Beijing 100083, China)Milk is considered an important source of protein in human diets. As the major protein component in milk, casein has attracted extensive attention from scholars due to its biparental structure and self-assembly properties. However, the poor pH, Ca2+, and temperature stability of casein micelles limit their application in delivery systems. This article systematically introduces the structural types of casein, the methods for its structural analysis, the methods for its modification based on the defects of micelle properties and their subsequent applications, aiming to prove the huge potential of casein micelles as delivery systems for bioactive compounds. Furthermore, this review provides an outlook on the future development of casein micelle systems in the field of functional food ingredients.https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-12-042.pdfcasein; micelle structure; encapsulation; hydrophobic bioactive substances; modification
spellingShingle YE Jingying, WU Fan, ZHANG Zhaoyue, WEN Xin, NI Yuanying, LI Mo
Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems
Shipin Kexue
casein; micelle structure; encapsulation; hydrophobic bioactive substances; modification
title Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems
title_full Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems
title_fullStr Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems
title_full_unstemmed Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems
title_short Research Progress on Structural Properties of Casein Micelles and Their Application in Delivery Systems
title_sort research progress on structural properties of casein micelles and their application in delivery systems
topic casein; micelle structure; encapsulation; hydrophobic bioactive substances; modification
url https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-12-042.pdf
work_keys_str_mv AT yejingyingwufanzhangzhaoyuewenxinniyuanyinglimo researchprogressonstructuralpropertiesofcaseinmicellesandtheirapplicationindeliverysystems