Synthetic Promoters in Gene Therapy: Design Approaches, Features and Applications

Synthetic Promoters in Gene Therapy: Design Approaches, Features and Applications

Gene therapy is a promising approach to the treatment of various inherited diseases, but its development is complicated by a number of limitations of the natural promoters used. The currently used strong ubiquitous natural promoters do not allow for the specificity of expression, while natural tissu...

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Bibliographic Details
Main Authors: Valentin Artemyev, Anna Gubaeva, Anastasiia Iu. Paremskaia, Amina A. Dzhioeva, Andrei Deviatkin, Sofya G. Feoktistova, Olga Mityaeva, Pavel Yu. Volchkov
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
synthetic promoters
gene therapy
promoter design
eukaryotic promoters
gene expression
Online Access:https://www.mdpi.com/2073-4409/13/23/1963
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