Decision tree model-based cost-effectiveness analysis of ligation for prolapsed hemorrhoids versus Ruiyun procedure for hemorrhoids for grade Ⅱ to Ⅲ prolapsed hemorrhoids
[Objectives] To evaluate the cost-effectiveness of ligation for prolapsed hemorrhoids versus Ruiyun procedure for hemorrhoids for grade Ⅱ to Ⅲ prolapsed hemorrhoids. [Methods] A cost-effectiveness model was built on a randomized controlled trial conducted at the Putuo Hospital Affiliated to Shanghai...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Colorectal & Anal Surgery
2022-06-01
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| Series: | 结直肠肛门外科 |
| Subjects: | |
| Online Access: | https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=410&cateName=2022%E5%B9%B4%20%E7%AC%AC28%E5%8D%B7%20%E7%AC%AC3%E6%9C%9F |
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| Summary: | [Objectives] To evaluate the cost-effectiveness of ligation for prolapsed hemorrhoids versus Ruiyun procedure for hemorrhoids for grade Ⅱ to Ⅲ prolapsed hemorrhoids. [Methods] A cost-effectiveness model was built on a randomized controlled trial conducted at the Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine between May 2018 and June 2021. In this trial, 66 patients with grade Ⅱ to Ⅲ prolapsed hemorrhoids were randomly assigned to the treatment group (n=33, receiving ligation for prolapsed hemorrhoids) and the control group (n=33, receiving Ruiyun procedure for hemorrhoids). Costs of hospitalization, and clinical data such as effectiveness were collected. A decision tree model was built with the Treeage Pro 2011. Model outputs included quality adjusted life years (QALYs), cost-effectiveness ratio (CER), and incremental cost-effectiveness ratio (ICER). One-way sensitivity analyses and probabilistic sensitivity analyses were performed. [Results] Cure rate was significantly higher in the treatment group than in the control group (P < 0.05). Compared to the control group, the treatment group had significantly lower hospitalization costs (P < 0.05) but similar QALYs gains (P > 0.05). CER in the treatment group was significantly lower than that in the control group (P < 0.05), indicating ligation for prolapsed hemorrhoids is more cost-effective. ICER was-119, 019.6 RMB/QALYs, indicates that the treatment group has a cost-effectiveness advantage. Sensitivity analyses showed similar results to base-case model results. [Conclusion] Compared with Ruiyun procedure for hemorrhoids, ligation for prolapsed hemorrhoids has a cost-effectiveness advantage. It has certain value of clinical promotion. |
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| ISSN: | 1674-0491 |